A light square against a dark background besides an equisized dark square against a light background shows a difference in apparent size such that the light square seems larger than the dark one. This illusion was studied for squares of 109 x 109 min arc. Their centres were located 90 min arc out of the centre of the fovea. The apparent size appeared to be dependent on the contrast between the square and the background and not on the mean luminance in the vicinity of the contour. The addition of a small white or dark line to the luminance step that constituted the border of the square changed the illusion dramatically. It is argued that this explains the observations where an inversion of the illusion for very small contrast values was found. The results are explained on the basis of a model with receptive fields of different sizes overlapping the same retinal location and having different sensitivities.
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http://dx.doi.org/10.1016/0042-6989(88)90183-6 | DOI Listing |
Mol Pharm
January 2025
Department of Pharmaceutics, School of Pharmacy, Virginia Commonwealth University, Richmond, Virginia 23298, United States.
Chemotherapy-induced peripheral neuropathy (CIPN) is a serious side effect of anticancer agents with limited effective preventive or therapeutic interventions. Although fenofibrate, a peroxisome proliferator-activated receptor-alpha (PPARα) agonist, has demonstrated neuroprotective and analgesic properties, its clinical utility is hindered by low receptor affinity, poor subtype selectivity, and suboptimal bioavailability. A190, a highly selective and potent nonfibrate PPARα agonist, offers a promising alternative but is limited by poor aqueous solubility, resulting in reduced oral bioavailability and therapeutic efficacy.
View Article and Find Full Text PDFWorld J Gastroenterol
January 2025
Department of Internal Medicine, Asahikawa Medical University, Asahikawa 078-8510, Hokkaido, Japan.
The challenge of effectively eliminating air during gastrointestinal endoscopy using ultrasound techniques is apparent. This difficulty arises from the intricacies of removing concealed air within the folds of the gastrointestinal tract, resulting in artifacts and compromised visualization. In addition, the overlap of folds with lesions can obscure their depth and size, presenting challenges for an accurate assessment.
View Article and Find Full Text PDFThe coupling effect of gamma-ray radiation and 532 nm nanosecond laser radiation on optical coatings and substrates was investigated. Fused silica and S-BSL7 glass with 532 nm high reflectivity (HR) coatings were irradiated using Co gamma-ray source at a dose rate of 1 Gy/s for a total dose of 1-500 kGy. After irradiation, the samples were subjected to raster scan testing using a laser with a pulse width of approximately 8.
View Article and Find Full Text PDFSci Rep
January 2025
PV Unit, Solar and Space Research Department, National Research Institute of Astronomy and Geophysics (NRIAG), Helwan, Cairo, Egypt.
The inadequate thermal insulation of the building envelope contributes significantly to the high power consumption of air conditioners in houses. A crucial factor in raising a building's energy efficiency involves utilizing bricks with high thermal resistance. This issue is accompanied by another critical challenge: recycling and disposing of waste in a way that is both economically and environmentally beneficial, including using it to fuel industrial growth, in order to reduce the harmful effects of waste on the environment as waste generation in our societies grows.
View Article and Find Full Text PDFAME Case Rep
January 2025
Department of Clinical Medicine, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Background: Thymolipomas are rare benign mediastinal tumors primarily occurring in young adults, although they can also present in pediatric populations. These tumors are often asymptomatic, but their substantial size can create significant diagnostic and therapeutic challenges, necessitating careful evaluation and management.
Case Description: A teenage girl was diagnosed with a giant thymolipoma, which was discovered incidentally during a routine chest radiograph.
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