Lumpy skin disease (LSD) is a devastating disease of cattle characterized by fever, nodules on the skin, lymphadenopathy and milk drop. Several haematophagous arthropod species like dipterans and ticks are suspected to play a role in the transmission of LSDV. Few conclusive data are however available on the importance of biting flies and horseflies as potential vectors in LSDV transmission. Therefore an in vivo transmission study was carried out to investigate possible LSDV transmission by Stomoxys calcitrans biting flies and Haematopota spp. horseflies from experimentally infected viraemic donor bulls to acceptor bulls. LSDV transmission by Stomoxys calcitrans was evidenced in 3 independent experiments, LSDV transmission by Haematopota spp. was shown in one experiment. Evidence of LSD was supported by induction of nodules and virus detection in the blood of acceptor animals. Our results are supportive for a mechanical transmission of the virus by these vectors.
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| http://dx.doi.org/10.1038/s41598-019-56605-6 | DOI Listing |
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Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER), via Bianchi 9, Brescia 24125, Italy. Electronic address:
Lumpy skin disease (LSD), caused by the LSD virus (LSDV) from the Capripoxvirus genus, affects cattle, water buffalo, and wild bovines, leading to significant economic losses. Characterised by fever, skin nodules, and mucosal lesions, LSD raises global concerns due to vector-borne transmission. The World Organisation for Animal Health (WOAH) classifies LSD as a notifiable disease, emphasising the need for rapid diagnostic methods for timely disease confirmation and control.
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College of Veterinary Medicine & Bio-Safety Research Institute, Jeonbuk National University, Iksan 54596, Republic of Korea.
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Department of Bioinformatics, College of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, 141004, India.
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Department of Parasitology and Animal Diseases, National Research Centre, 33 Bohouth Street, Dokki, Giza, 12622, Egypt.
Article Synopsis
- Lumpy skin disease (LSD) is a viral infection causing significant economic impacts on cattle and buffalo populations in Egypt, prompting a study to explore its recent outbreaks and transmission methods.
- Researchers collected various samples from cattle and buffaloes, including skin biopsies, nasal swabs, blood, and hard ticks, using advanced molecular techniques like multiplex PCR and real-time quantitative PCR to analyze the data.
- The study found a high prevalence of LSDV in the sampled animals and confirmed that hard ticks (Rhipicephalus annulatus) are likely involved in the spread of the virus, marking an important step in understanding and controlling the disease.
A new variant of lumpy skin disease virus circulating in Vietnam based on sequencing analysis of GPCR gene.
Open Vet J
July 2024
Department of Biochemistry and Immunology, National Institute of Veterinary Research, Hanoi, Vietnam.
Background: In 2021, Vietnam experienced an outbreak of Lumpy skin disease (LSD), which infected 207,687 cattle and buffaloes, as officially reported, and resulted in the culling of 29,182 animals.
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Methods: Three methods recommended by WOAH for agent detection (PCR, virus isolation, and transmission electron microscopy) were used to confirm this clinical LSD case.
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