Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/MPG.0000000000002610 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Dexamethasone Delivery via Amphiphilic, Low-swelling Hydrogels Treats Postoperative Inflammation in Cervical Spine Applications.
Adv Healthc Mater
January 2025
Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, 30332-0363, USA.
Anterior cervical spine surgeries are often complicated by difficulty swallowing due to local postoperative swelling, pain, scarring, and tissue dysfunction. These postoperative events lead to systemic steroid and narcotic use. Local, sustained drug delivery may address these problems, but current materials are unsafe for tight surgical spaces due to high biomaterial swelling, especially upon degradation.
View Article and Find Full Text PDFACG Clinical Guideline: Diagnosis and Management of Eosinophilic Esophagitis.
Am J Gastroenterol
January 2025
Kennth C. Griffin Esophageal Center, Division of Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Article Synopsis
- Eosinophilic esophagitis (EoE) is a chronic immune disease characterized by symptoms of esophageal dysfunction and an eosinophil-dominated infiltration in the esophagus.
- The incidence of EoE is rising, requiring attention in various medical settings, leading to updated guidelines that focus on improved diagnosis and treatment strategies.
- Recommended treatments include proton pump inhibitors, topical steroids, dietary elimination, and esophageal dilation, with an emphasis on monitoring patients for treatment response and managing both inflammatory and structural aspects of the disease.
First Case Report of Bilateral Avascular Necrosis in an Eosinophilic Esophagitis Patient on Swallowed Fluticasone.
Cureus
November 2024
Gastroenterology and Hepatology, Sheikh Shakhbout Medical City, Abu Dhabi, ARE.
Article Synopsis
- * A 28-year-old man with worsening EoE symptoms, treated with fluticasone via inhaler for seven years, developed limping and groin pain leading to hip replacements after MRI confirmed bilateral AVN.
- * After stopping the inhaled steroid and starting dupilumab treatment, the patient’s EoE symptoms improved significantly, highlighting the importance of recognizing potential serious side effects of topical corticosteroids among healthcare professionals.
A novel variant BCL11B mutation in a pediatric patient with difficult-to-treat eosinophilic esophagitis.
JPGN Rep
November 2024
Division of Pediatric Gastroenterology, Hepatology, and Nutrition Vanderbilt University Medical Center Nashville Tennessee USA.
Article Synopsis
- * The patient underwent extensive treatment, including multiple procedures and medications, achieving remission with a combination of swallowed steroids and high-dose proton pump inhibitors (PPIs), but faced a relapse when attempting to reduce PPI use.
- * This case highlights the potential benefits of genetic testing for patients with hard-to-treat EoE and raises important questions about treatment strategies and goals for affected children with genetic mutations.
Daily or Twice Daily Treatment with Topical Steroids Results in Similar Responses in Eosinophilic Esophagitis.
Clin Gastroenterol Hepatol
November 2024
Center for Esophageal Diseases and Swallowing, Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina; Center for Gastrointestinal Biology and Disease, Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina. Electronic address:
Background & Aims: Few data compare topical corticosteroid (tCS) dosing regimens and outcomes. We aimed to compare treatment outcomes in patients with eosinophilic esophagitis (EoE) by once or twice daily dosing regimens.
Methods: We conducted a retrospective cohort study using the UNC EoE Clinicopathologic Database of newly diagnosed patients with EoE treated with a tCS who had a follow-up endoscopy with biopsy.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!