Neutropenic enterocolitis (NE) is a life-threatening infection of the immunocompromised. NE ubiquitously affects the cecum, often with involvement of the ascending colon and ileum. Classically, NE is associated with high mortality leading to the frequent use of aggressive treatment strategies including surgery. Although conservative approaches are often successful, there are currently no standardized treatment guidelines for NE and it is unclear when such strategies should be implemented. Here, we describe a patient with suspected chemotherapy-associated NE despite having previously undergone a right hemicolectomy. As computed tomography imaging failed to provide a conclusive diagnosis, we performed a gentle endoscopic evaluation that affirmed a diagnosis of NE of the transverse colon, and suggested the patient would benefit from conservative treatment. This case demonstrates that endoscopy can be a safe and useful tool in the diagnosis of NE, and is an important reminder that NE can affect any part of the gastrointestinal tract.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924534 | PMC |
http://dx.doi.org/10.1093/omcr/omz140 | DOI Listing |
Case Rep Gastrointest Med
December 2024
Shiraz Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Esophageal embryonal rhabdomyosarcoma (ERMS), a rare pediatric cancer, mimicked achalasia in a case involving dysphagia and vomiting. Diagnosis and chemotherapy necessitate careful monitoring due to potential complications. A 12-year-old girl with no prior medical history presented with progressive dysphagia and vomiting.
View Article and Find Full Text PDFCureus
October 2024
Department of Pathology, College of Medicine, Qatar University, Doha, QAT.
Neutropenic enterocolitis (NE) is a potentially life-threatening condition, primarily affecting neutropenic patients with hematologic malignancies. The clinical manifestations of NE in patients receiving antineoplastic drugs range from fever, diarrhea, nausea, vomiting, and abdominal pain to intestinal perforation and shock. We report the case of a 12-year-old boy with acute myelogenous leukemia, undergoing chemotherapy, who presented with an atypical case of NE.
View Article and Find Full Text PDFCureus
September 2024
Internal Medicine, University of Miami at Holy Cross, Fort Lauderdale, USA.
Risk Anal
October 2024
Department of Biosystems and Agricultural Engineering, Michigan State University, East Lansing, Michigan, USA.
Acta Vet Scand
July 2024
Department of Pathology, Faculty of Veterinary Medicine, Cairo University, PO Box 12211, Giza, Egypt.
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