We present field-experiment support for the feasibility of post-detection restoration when imaging through deep turbulence characterized by extreme anisoplanatism. Short-exposure images of point-like and minimally extended objects (MEOs) were collected, viewed through a 5.1-kilometer atmospheric path producing isoplanatic angles roughly 1/15 the camera diffraction-limited angular resolution. A correlation-based isoplanatic angle measurement technique is presented along with data verifying deep-turbulence conditions. In agreement with prior wave-optics simulations, the experiments demonstrate short-exposure images of MEOs retain a central lobe that is clearly narrower than the long-exposure counterpart, even in the presence of severe anisoplanatism. New simulations are presented to provide direct comparison with measurements of point-like and MEO image central lobe radius statistics.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1364/OE.27.032938 | DOI Listing |
Javed E, Thangavel C, Frara N, et al. Increased expression of desmin and vimentin reduces bladder smooth muscle contractility via JNK2. The FASEB Journal.
View Article and Find Full Text PDFBiosens Bioelectron
February 2025
Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Analytical Chemistry for Living Biosystems, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China; School of Chemical Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address:
Metal-biomolecule interactions that are ubiquitous in nature provide fundamental knowledge and rich structural motifs for the development of functional molecules and smart sensors. In this work, inspired by the active sites in metalloproteins, a biomimetic peptide sensor was designed for the selective recognition and activatable sensing of Hg in living biosystems. Tetraphenylethylene (TPE) with typical aggregation-induced emission (AIE) behavior, was introduced as the activatable signal transducer to enable high signal-to-background signaling.
View Article and Find Full Text PDFTrials
October 2024
Centre for Health Informatics, Division of Informatics, Imaging and Data Science, University of Manchester, Manchester Academic Health Science Centre, Vaughan House, Portsmouth Street, Manchester, M13 9GB, UK.
Background: Management of rheumatoid arthritis (RA) relies on symptoms reported by patients during infrequent outpatient clinic visits. These reports are often incomplete and inaccurate due to poor recall, leading to suboptimal treatment decisions and outcomes. Asking people to track symptoms in-between visits and integrating the data into clinical pathways may improve this.
View Article and Find Full Text PDFLight Sci Appl
May 2024
Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, 100871, China.
Structured illumination microscopy (SIM) has emerged as a promising super-resolution fluorescence imaging technique, offering diverse configurations and computational strategies to mitigate phototoxicity during real-time imaging of biological specimens. Traditional efforts to enhance system frame rates have concentrated on processing algorithms, like rolling reconstruction or reduced frame reconstruction, or on investments in costly sCMOS cameras with accelerated row readout rates. In this article, we introduce an approach to elevate SIM frame rates and region of interest (ROI) coverage at the hardware level, without necessitating an upsurge in camera expenses or intricate algorithms.
View Article and Find Full Text PDFVolumetric functional imaging of transient cellular signaling and motion dynamics poses a significant challenge to current microscopy techniques, primarily due to limitations in hardware bandwidth and the restricted photon budget within short exposure times. In response to this challenge, we present squeezed light field microscopy (SLIM), a computational imaging method that enables rapid detection of high-resolution three-dimensional (3D) light signals using only a single, low-format camera sensor area. SLIM pushes the boundaries of 3D optical microscopy, achieving over one thousand volumes per second across a large field of view of 550 μm in diameter and 300 μm in depth with a spatial resolution of 3.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!