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Inhibitory Effect of Osthole from on Tobacco Mosaic Virus (TMV) Infection in . | LitMetric

AI Article Synopsis

Article Abstract

The coumarin compound of osthole was extracted from and identified by LC-MS and H- and C-NMR. Osthole was tested for anti-virus activity against tobacco mosaic virus (TMV) using the half-leaf method. The results showed that stronger antiviral activity on TMV infection appeared in than that of eugenol and ningnanmycin, with inhibitory, protective, and curative effects of 72.57%, 70.26%, and 61.97%, respectively. Through observation of the TMV particles, we found that osthole could directly affect the viral particles. Correspondingly, the level of coat protein detected by Western blot was significantly reduced when the concentrations of osthole increased in tested plants compared to that of the control. These results suggest that osthole has anti-TMV activity and may be used as a biological reagent to control the plant virus in the half-leaf method.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982833PMC
http://dx.doi.org/10.3390/molecules25010065DOI Listing

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