Radioactive contamination is a highly concerning global environmental issue along with the development of the nuclear industry. On account of sophisticated operations and high cost of instrument detection methods, numerous efforts have been focused on rapid and simple detection of pollution elements and uranium is the most common one. It is an enormous challenge to push the limit of determination as low as possible while carrying out ultrasensitive detection. Here, we report an intelligent platform based on functionalized solid nanochannels to monitor ultratrace uranyl ions. The platform has a detection limit of 1 fM, which is far below the value that traditional instrumental methods can reach. What is more, the system also exhibits uranyl removal property. The mesenchymal stem cells cultivated in media containing uranyl can achieve excellent viability in the presence of the membranes. This work provides a new choice for handling global radioactive contamination of water.
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