A new flavone( 1) has been isolated from the whole plant of Cassia nomame by using various chromatographic techniques,including silica gel,Sephadex,MCI-gel resin,and RP-HPLC,and its structure was determined as 8,4'-dimethoxy-7-( 2-oxopropyl)-flavone based on spectroscopic data. The biological activity test showed that this compound displayed potent cytotoxicity against NB4,SH-SY5 Y,PC3,A549 and MCF-7 cell lines with IC values 2. 2,1. 8,3. 4,4. 5 and 1. 6 μmol·L,respectively.
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| http://dx.doi.org/10.19540/j.cnki.cjcmm.20190716.201 | DOI Listing |
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