The histocompatibility and immunogenetics of hand transplantation.

Int J Immunogenet

Department of Plastic and Reconstructive Surgery, Leeds Teaching Hospitals, Leeds, UK.

Published: February 2020

This short review will be concerned with the literature that has developed connected with the immunogenetic and tissue compatibility aspects of hand transplantation and will also draw on connected work in the more general area of vascularized composite allotransplantation (VCA) which includes face, abdominal wall uterus and larynx.

Download full-text PDF

Source
http://dx.doi.org/10.1111/iji.12469DOI Listing

Publication Analysis

Top Keywords

hand transplantation
8
histocompatibility immunogenetics
4
immunogenetics hand
4
transplantation short
4
short review
4
review will
4
will concerned
4
concerned literature
4
literature developed
4
developed connected
4

Similar Publications

In recent years, novel therapeutic approaches have revolutionized the landscape of medicine, offering promising avenues for the cure of various diseases. The novel approaches explore advancements in gene therapy in pharmaceuticals, immunotherapy, RNA-based therapeutics, cell-based therapies, and targeted tumor therapies. Gene therapy has emerged as a groundbreaking approach, leveraging genetic material to cure or prevent diseases by targeting defective genes.

View Article and Find Full Text PDF

Vascularised Composite Allotransplantation - A guide to optimal dissemination of scientific outputs.

J Hand Microsurg

January 2025

Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, Dublin, Ireland.

Purpose: The impact of academic research is not just important within the clinical domain but within society as a whole. Altmetric Attention Score (AAS) offers a means of assessing how scholarly outputs are interacted with online. Vascularised Composite Allotransplantation (VCA) is a modern but rapidly evolving topic which encompasses a broad range of complex and clinically significant surgical interventions.

View Article and Find Full Text PDF

Designer Organs: Ethical Genetic Modifications in the Era of Machine Perfusion.

Annu Rev Biomed Eng

January 2025

1Center for Engineering for Medicine and Surgery, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA;

Gene therapy is a rapidly developing field, finally yielding clinical benefits. Genetic engineering of organs for transplantation may soon be an option, thanks to convergence with another breakthrough technology, ex vivo machine perfusion (EVMP). EVMP allows access to the functioning organ for genetic manipulation prior to transplant.

View Article and Find Full Text PDF

Introduction: Health-related quality of life (HR-QoL) outcomes following maxillary reconstruction with the scapular osseous free flap (SOFF) are lacking.  Material and Methods: To determine these outcomes, a study of patients who completed maxillary reconstruction with flap survival of the SOFF between 2016 and 2023 was conducted, using Face-Q Head and Neck Cancer Module (FACE-Q).

Results: Eligible patients had at least six months of follow-up.

View Article and Find Full Text PDF

Retinal graft dislocation managed by repeat autologous retinal transplant for refractory macular hole.

BMJ Case Rep

January 2025

Smt. Kanuri Santhamma Centre for Vitreo Retinal Diseases, Anant Bajaj Retina Institute, LV Prasad Eye Institute, Hyderabad, Telangana, India

A septuagenarian man presented with a visual acuity of hand motions and a large refractory macular hole (MH). We performed an autologous retinal transplant (ART) and covered the graft with fibrin glue without any endotamponade. The autograft was found to have dislocated from the MH when the patient was reviewed 1 week later.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!