The production of biodegradable polymers as alternatives to petroleum-based plastics has gained significant attention in the past years. To this end, polylactic acid (PLA) constitutes a promising alternative, finding various applications from food packaging to pharmaceuticals. Recent studies have shown that d-lactic acid plays a vital role in the production of heat-resistant PLA. At the same time, the utilization of renewable resources is imperative in order to decrease the production cost. This review aims to provide a synopsis of the current state of the art regarding d-lactic acid production fermentation, focusing on the exploitation of waste and byproduct streams. An overview of potential downstream separation schemes is also given. Additionally, three case studies are presented and discussed, reporting the obtained results utilizing acid whey, coffee mucilage and hydrolysate from rice husks as alternative feedstocks for d-lactic acid production.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902291PMC
http://dx.doi.org/10.17113/ftb.57.03.19.6023DOI Listing

Publication Analysis

Top Keywords

d-lactic acid
16
acid production
12
renewable resources
8
case studies
8
acid
6
production
6
advances d-lactic
4
production renewable
4
resources case
4
studies agro-industrial
4

Similar Publications

Machine learning applications in healthcare clinical practice and research.

World J Clin Cases

January 2025

Department of Gastroenterology, Laiko General Hospital, National and Kapodistrian University of Athens, Athens 11527, Greece.

Machine learning (ML) is a type of artificial intelligence that assists computers in the acquisition of knowledge through data analysis, thus creating machines that can complete tasks otherwise requiring human intelligence. Among its various applications, it has proven groundbreaking in healthcare as well, both in clinical practice and research. In this editorial, we succinctly introduce ML applications and present a study, featured in the latest issue of the .

View Article and Find Full Text PDF

Application of the SpCas9 inhibitor BRD0539 for CRISPR/Cas9-based genetic tools in .

Biosci Microbiota Food Health

September 2024

Department of Agricultural Chemistry, Graduate School of Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan.

Although the clustered regularly interspaced short palindromic repeat (CRISPR)-Cas system has been extensively developed since its discovery for eukaryotic and prokaryotic genome editing and other genetic manipulations, there are still areas warranting improvement, especially regarding bacteria. In this study, BRD0539, a small-molecule inhibitor of Cas9 (SpCas9), was used to suppress the activity of the nuclease during genetic modification of , as well as to regulate CRISPR interference (CRISPRi). First, we developed and validated a CRISPR-SpCas9 system targeting the gene of .

View Article and Find Full Text PDF

α-Lipoic acid increases phagocytosis of some lactic acid bacteria via modulation of CD36 expression.

Biosci Microbiota Food Health

August 2024

Local Brand R&D, SSP Co., Ltd., Opera City Tower, 3-20-2 Nishi Shinjuku, Shinjuku-ku, Tokyo 163-1488, Japan.

Phagocytosis by immunocompetent cells is a key role in the biological defense mechanism and is the starting point of the reaction that leads from innate to acquired immunity. Several studies have demonstrated that some lactic acid bacteria strains activate the innate and acquired immune systems of the host. However, further investigation of the mechanism and improvement of usefulness is needed because the effect differs depending on the type and strain of lactic acid bacteria.

View Article and Find Full Text PDF

Impact of container type on the microbiome of airag, a Mongolian fermented mare's milk.

Biosci Microbiota Food Health

October 2024

Division of Systems Bioengineering, Department of Bioresource and Biotechnology, Faculty of Agriculture, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.

Airag, a fermented mare's milk in Mongolia, exhibits diverse flavors and microbiota due to distinct production processes and environments in nomadic households. Recently, there has been a shift from the traditional cow skin container, 'khokhuur', to a plastic container for airag production, potentially impacting the microbiota and quality. To address this notion, we aimed to elucidate the differences in the microbiota between airag samples from a plastic container and those from a khokhuur.

View Article and Find Full Text PDF

Effects of moderate beer consumption on immunity and the gut microbiome in immunosuppressed mice.

Biosci Microbiota Food Health

August 2024

Department of Microecology, College of Basic Medical Sciences, Dalian Medical University, Dalian 116044, PR China.

Beer contains a variety of bioactive ingredients and trace elements that can regulate bodily functions, and moderate consumption of beer can enhance immune responses. This study aimed to investigate the potential benefits of moderate consumption of alcoholic or non-alcoholic beer on the gut microbiome, immunity, and intestinal barrier function in immunosuppressed BALB/c mice induced by cyclophosphamide (CTX). Model mice with CTX-induced immunosuppression were administered alcoholic or non-alcoholic beer or galacto-oligosaccharides (GOS) for 28 consecutive days.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!