AI Article Synopsis
- * Only 1.1% of the IDPs were found to be upgraded to ductal carcinoma in situ or invasive carcinoma during excision, indicating a low risk of malignancy.
- * Factors influencing upgrade rates included age, size of the papilloma on biopsy, and presence of additional ultrasound masses, suggesting that monitoring rather than immediate surgery may be sufficient for certain benign cases.
Article Abstract
Context: Surgical excision of benign intraductal papillomas (IDP) diagnosed on core needle biopsy (CNB) remains controversial.
Objective: To examine the upgrade rate of IDPs diagnosed at core needle biopsy to carcinoma at surgical excision.
Design: We identified 188 consecutive IDPs diagnosed at CNB from 2011 to 2016 with subsequent surgical excision. Radiologic, clinical, and histologic features were evaluated and correlated with upgrade rate at surgical excision.
Results: Two of the 188 IDPs (1.1%) were upgraded to ductal carcinoma in situ or invasive carcinoma at excision. Features associated with upgrade rate include patient age (P = .03), largest size of papilloma on a single core at CNB (P = .04), and the presence of additional masses noted at ultrasound (P = .03).
Conclusions: Our study demonstrated a low 1.1% upgrade rate of surgically excised benign, concordant papillomas with no atypia or concurrent ipsilateral malignancy originally diagnosed on core biopsy. This data suggests that observation may be appropriate for radiologic-pathologic concordant benign IDPs diagnosed at CNB.
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| http://dx.doi.org/10.1016/j.clinimag.2019.10.009 | DOI Listing |
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