Vehicular ad hoc networks (VANETs) are the key enabling technology for intelligent transportation systems. Carrier-sense multiple access with collision avoidance (CSMA/CA) is the de facto media access standard for inter-vehicular communications, but its performance degrades in high-density networks. Time-division multiple access (TDMA)-based protocols fill this gap to a certain extent, but encounter inefficient clock synchronization and lack of prioritized message delivery. Therefore, we propose a priority-based direction-aware media access control (PDMAC) as a novel protocol for intra-cluster and inter-cluster clock synchronization. Furthermore, PDMAC pioneers a three-tier priority assignment technique to enhance warning messages delivery by taking into account the direction component, message type, and severity level on each tier. Analytical and simulation results validate the improved performance of PDMAC in terms of clock synchronization, channel utilization, message loss rate, end-to-end delays, and network throughput, as compared with eminent VANET MAC protocols.
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http://dx.doi.org/10.3390/s20010045 | DOI Listing |
R Soc Open Sci
January 2025
School of Mathematics & Statistics, University of Sydney, Sydney, New South Wales 2006, Australia.
Lymphatic system failures contribute to cardiovascular and various other diseases. A critical function of the lymphatic vascular system is the active pumping of fluid from the interstitium back into the blood circulation by periodic contractions of lymphatic muscle cells (LMCs) in the vessel walls. As in cardiac pacemaking, these periodic contractions can be interpreted as occurring due to linked pacemaker oscillations in the LMC membrane potential (M-clock) and calcium concentration (C-clock).
View Article and Find Full Text PDFPLoS Genet
January 2025
School of Life Sciences, Gansu Key Laboratory of Biomonitoring and Bioremediation for Environmental Pollution, Lanzhou University, Lanzhou, China.
A key property of the circadian clock is that it is reset by light to remain synchronized with the day-night cycle. An attractive model to explore light input to the circadian clock in vertebrates is the zebrafish. Circadian clocks in zebrafish peripheral tissues and even zebrafish-derived cell lines are entrainable by direct light exposure thus providing unique insight into the function and evolution of light regulatory pathways.
View Article and Find Full Text PDFAnimals (Basel)
December 2024
Centro de Investigaciones Biomédicas, Universidad Veracruzana, Xalapa 91090, Veracruz, Mexico.
The suprachiasmatic nucleus (SCN) is the master regulator of the circadian system, modulating the daily timing of physiological and behavioral processes in mammals. While SCN synchronization is primarily driven by environmental light signals, sex hormones, particularly androgens, have a crucial role in regulating behavioral and reproductive processes to align with daily or seasonal cycles. SCN cell populations express receptors for sex steroid hormones, contributing to circadian synchronization mechanisms.
View Article and Find Full Text PDFMed Res Rev
January 2025
Centre for Systems Chemistry, Stratingh Institute for Chemistry, University of Groningen, Groningen, The Netherlands.
Circadian rhythms are endogenous biological oscillators that synchronize internal physiological processes and behaviors with external environmental changes, sustaining homeostasis and health. Disruption of circadian rhythms leads to numerous diseases, including cardiovascular and metabolic diseases, cancer, diabetes, and neurological disorders. Despite the potential to restore healthy rhythms in the organism, pharmacological chronotherapy lacks spatial and temporal resolution.
View Article and Find Full Text PDFBiomed J
January 2025
ٰLaboratorio de Cronobiología, Departamento de Ciencia y Tecnología, Universidad Nacional de Quilmes/CONICET. Buenos Aires, Argentina. Electronic address:
The circadian system is composed by a central hypothalamic clock at the suprachiasmatic nuclei (SCN) that communicates with peripheral circadian oscillators for daily coordination of behavior and physiology. The SCN entrain to the environmental 24-h light-dark (LD) cycle and drive daily rhythms of internal synchronizers such as core body temperature, hypothalamic-hypophysary hormones, sympathetic/parasympathetic activity, as well as behavioral and feeding-fasting rhythms, which supply signals setting core molecular clocks at central and peripheral tissues. Steady phase relationships between the SCN and peripheral oscillators keep homeostatic processes such as microbiota/microbiome composition/activity, metabolic supply/demand, energy balance, immunoinflammatory process, sleep amount and quality, psychophysiological stress, etc.
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