Purpose: The model used to calculate dose distributions in a radiotherapy treatment plan relies on the data entered during beam commissioning. The quality of these data heavily depends on the detector choice made, especially in small fields and in the buildup region. Therefore, it is necessary to identify suitable detectors for measurements in the buildup region of small fields. To aid the understanding of a detector's limitations, several factors that influence the detector signal are to be analyzed, for example, the volume effect due to the detector size, the response to electron contamination, the signal dependence on the polarity used, and the effective point of measurement chosen.
Methods: We tested the suitability of different small field detectors for measurements of depth dose curves with a special focus on the surface-near area of dose buildup for fields sized between 10 × 10 and 0.6 × 0.6 cm . Depth dose curves were measured with 14 different detectors including plane-parallel chambers, thimble chambers of different types and sizes, shielded and unshielded diodes as well as a diamond detector. Those curves were compared with depth dose curves acquired on Gafchromic film. Additionally, the magnitude of geometric volume corrections was estimated from film profiles in different depths. Furthermore, a lead foil was inserted into the beam to reduce contaminating electrons and to study the resulting changes of the detector response. The role of the effective point of measurement was investigated by quantifying the changes occurring when shifting depth dose curves. Last, measurements for the small ionization chambers taken at opposing biasing voltages were compared to study polarity effects.
Results: Depth-dependent correction factors for relative depth dose curves with different detectors were derived. Film, the Farmer chamber FC23, a 0.13 cm scanning chamber CC13 and a plane-parallel chamber PPC05 agree very well in fields sized 4 × 4 and 10 × 10 cm . For most detectors and in smaller fields, depth dose curves differ from the film. In general, shielded diodes require larger corrections than unshielded diodes. Neither the geometric volume effect nor the electron contamination can account for the detector differences. The biggest uncertainty arises from the positioning of a detector with respect to the water surface and from the choice of the detector's effective point of measurement. Depth dose curves acquired with small ionization chambers differ by over 15% in the buildup region depending on sign of the biasing voltage used.
Conclusions: A scanning chamber or a PPC40 chamber is suitable for fields larger than 4 × 4 cm . Below that field size, the microDiamond or small ionization chambers perform best requiring the smallest corrections at depth as well as in the buildup region. Diode response changes considerably between the different types of detectors. The position of the effective point of measurement has a huge effect on the resulting curves, therefore detector specific rather than general shifts of half the inner radius of cylindrical ionization chambers for the effective point of measurement should be used. For small ionization chambers, averaging between both polarities is necessary for data obtained near the surface.
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http://dx.doi.org/10.1002/mp.13973 | DOI Listing |
Biomed Phys Eng Express
January 2025
Mindanao Radiation Physics Center, MSU-Iligan Institute of Technology, Andres Bonifacio Street Tibanga, Iligan City, Lanao Norte, 9200, PHILIPPINES.
To accurately model and validate the 6 MV Elekta Compactlinear accelerator using the Geant4 Application for Tomographic Emission (GATE). In particular, this study focuses on the precise calibration and validation of critical parameters, including jaw collimator positioning, electron source nominal energy, flattening filter geometry, and electron source spot size, which are often not provided in technical documentation. Methods: Simulation of the Elekta Compact6 MV linear accelerator was performed using the Geant4 Application for Tomographic Emission (GATE) v.
View Article and Find Full Text PDFAppl Radiat Isot
January 2025
Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, 230031, China. Electronic address:
This study investigated the influence of tissue electron density on proton beam dose distribution using TOPAS Monte Carlo simulation. Heterogeneous tissue models composed of 14 materials were constructed to simulate the dose deposition process of a 169.23 MeV proton beam.
View Article and Find Full Text PDFAnimals (Basel)
December 2024
College of Animal Science and Technology, Yangzhou University, Yangzhou 215009, China.
The aim of this study was to investigate the effects of terpinen-4-ol (TER) supplementation on the intestinal barrier function of pigs. Five groups of fifty 28-day-old piglets with comparable body weights were randomly assigned to the following groups: the control group (CON), the lipopolysaccharide group (LPS), the low TER group (PLT), the middle TER group (PMT), and the high TER group (PHT). The basal diet was given to the CON and LPS groups, and 30, 60, or 90 mg/kg TER was added to the basal diet for the TER groups.
View Article and Find Full Text PDFMed Dosim
January 2025
Department of Radiation Oncology, University of Rochester Medical Center, Rochester, NY.
Purpose: In radiotherapy treatment planning systems, modelling of superficial dose may be aided by a body contour that is, by default, placed at the outermost air-tissue interface. Here we investigate the accuracy of superficial dose calculated using either the default body contour (DBC) or an extended body contour (EBC) compared to radiochromic film measurements made on a slab phantom and an anthropomorphic phantom.
Methods: Depth dose curves in the superficial region of the slab phantom were measured using stacked radiochromic films and irradiated using static beams delivered from varying incident angles.
Appl Radiat Isot
January 2025
Kyoto University Graduate School of Engineering, Kyoto Daigaku-katsura, Nishikyo-ku, Kyoto, 615-8530, Japan.
We aimed to explore the possibility of realizing a beam shaping assembly (BSA) driven by a 15-kW beam of 33-MeV electrons of an electron linear accelerator (LINAC) when a boronophenylalanine is adopted as a boron carrier. Simulation calculations were performed to design two types of BSAs driven by the small LINAC. The one was an experimental BSA, and the other was a high-performance BSA.
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