Organizational settings are replete with changing stimulus contexts and contingencies, which makes relapse a particularly relevant framework for understanding the ways in which controlling stimuli influence employee responding. The purpose of the current study was to develop a translational model to assess renewal of desirable behavior in a simulated workplace with neurotypical adults. Experiment 1 assessed renewal of desirable behavior using a computerized check processing task. Experiment 2 extended the findings and the translational utility of the experimental arrangement to implementation of a behavior-analytic teaching procedure. Results across both experiments demonstrated renewal of desirable behavior. Overall, the current methodology and findings extend the human operant literature on renewal and demonstrate a translational model that brings together operant renewal and organizational behavior management.
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http://dx.doi.org/10.1002/jeab.566 | DOI Listing |
Int J Mol Sci
December 2024
Ocular Genomics Institute, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA.
Prime editing (PE) is a CRISPR-based tool for genome engineering that can be applied to generate human induced pluripotent stem cell (hiPSC)-based disease models. PE technology safely introduces point mutations, small insertions, and deletions (indels) into the genome. It uses a Cas9-nickase (nCas9) fused to a reverse transcriptase (RT) as an editor and a PE guide RNA (pegRNA), which introduces the desired edit with great precision without creating double-strand breaks (DSBs).
View Article and Find Full Text PDFSci Rep
January 2025
School of Electrical and Photoelectronic Engineering, West Anhui University, Lu'an, 237012, China.
The black-winged kite algorithm (BKA) constructed on the black-winged kites' migratory and predatory instincts is a revolutionary swarm intelligence method that integrates the Leader tactic with the Cauchy variation procedure to retrieve the expansive appropriate convergence solution. The essential BKA exhibits marginalized resolution efficiency, inferior assessment precision, and stagnant sensitive anticipation. To foster aggregate discovery intensity and advance widespread computational efficacy, an innovative complex-valued encoding BKA (CBKA) is presented to resolve the global optimization.
View Article and Find Full Text PDFBMC Biotechnol
December 2024
Institute of Food Biotechnology and Genomics of National Academy of Sciences of Ukraine, 2a Baidy-Vyshnevetskoho str., Kyiv, 04123, Ukraine.
Background: False flax, or gold-of-pleasure (Camelina sativa) is an oilseed that has received renewed research interest as a promising vegetable oil feedstock for liquid biofuel production and other non-food uses. This species has also emerged as a model for oilseed biotechnology research that aims to enhance seed oil content and fatty acid quality. To date, a number of genetic engineering and gene editing studies on C.
View Article and Find Full Text PDFIndian J Med Res
December 2024
ICMR-National Institute of Occupational Health, Ahmedabad, Gujarat, India.
Enteric fever is caused by the infection of Gram-negative bacteria, Salmonella enterica serovar Typhi and Salmonella enterica serovar Paratyphi (S. Paratyphi) A, B and C, through contaminated food and water. The disease almost exclusively affects the populations living in low- and middle-income countries, with the World Health Organization Southeast Asian Region (WHO SEAR) having the highest endemicity.
View Article and Find Full Text PDFJ Phys Chem Lett
December 2024
State Key Laboratory of Structural Analysis for Industrial Equipment & School of Physics, Dalian University of Technology, Dalian, Liaoning 116024 People's Republic of China.
An in-depth study of the substrate effect is crucial for optimizing and designing the performance of two-dimensional (2D) materials in practical applications. Fullerene monolayers (FMs), a new pure carbon system successfully prepared recently, have prompted renewed interest in the question of whether FMs might be exploited to create carbon-based functional materials with improved performance. Here, the electronic structure of a MXene-supported FM was investigated by first-principles calculations.
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