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Regional action needed to halt antimalarial drug resistance in Africa.
Lancet
January 2025
Mahidol Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok 10400, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK; WorldWide Antimalarial Resistance Network, Oxford, UK. Electronic address:
Approaching onchocerciasis elimination in Equatorial Guinea: Near zero transmission and public health implication.
Infect Dis Poverty
November 2024
National Centre for Tropical Medicine, Institute of Health Carlos III (ISCIII in Spanish), Madrid, Spain.
Article Synopsis
- Onchocerciasis and lymphatic filariasis (LF) are diseases prevalent in Equatorial Guinea, with efforts historically focused on Bioko Island, which has successfully interrupted onchocerciasis transmission, prompting a need to assess mainland regions where transmission status is unclear.
- The study, conducted from September to December 2019, employed various diagnostic methods on a sample of 3,951 individuals to estimate the prevalence of these diseases on the mainland, marking the first cross-sectional analysis for this area.
- Results showed a very low onchocerciasis seroprevalence of 0.3%, and while no O. volvulus microfilariae were found in biopsies, DNA evidence confirmed its presence in one
An integrated active case detection and management of skin NTDs in yaws endemic health districts in Cameroon, Côte d'Ivoire and Ghana.
PLoS Negl Trop Dis
October 2024
Clinical Research Department, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Article Synopsis
- Integrated approaches to mapping skin Neglected Tropical Diseases (NTDs) may optimize resource allocation, but extensive data covering multiple endemic countries was previously lacking.
- Between March 2021 and March 2023, integrated case searches were conducted in Cameroon, Côte d'Ivoire, and Ghana, screening over 61,000 individuals for various skin conditions including yaws and other NTDs.
- The findings revealed that 18.6% of those screened had skin lesions, with the majority being children; yaws was confirmed in a varying proportion of cases across the three countries, while scabies and fungal infections were the most commonly diagnosed conditions.
Clinical practice guidelines for the diagnosis and treatment of scabies.
Int J Dermatol
December 2024
Parasitology Unit, Department of Microbiology and Molecular Genetics, the Kuvin Center for the Study of Infectious and Tropical Diseases, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Scabies, caused by the Sarcoptes scabiei var hominis mite burrowing into the skin, is a highly contagious disease characterized by intense nocturnal itching. Its global impact is considerable, affecting more than 200 million individuals annually and posing significant challenges to healthcare systems worldwide. Transmission occurs primarily through direct skin-to-skin contact, contributing to its widespread prevalence and emergence as a substantial public health concern affecting large populations.
View Article and Find Full Text PDFDaphne genkwa: Ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine.
Fitoterapia
September 2024
Department of Pharmacy, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China; School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, Yunnan 650500, China; Department of Pharmacy Research, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China. Electronic address:
Daphne genkwa, as a traditional medicine, is widely distributed in China, Korea and Vietnam. In China, the dried flower buds of this plant are named "Yuanhua". It has the ability to effectively promote urination, eliminate phlegm and alleviate cough, eliminate parasites and cure of scabies, with a broad spectrum of pharmacological effects and considerable clinical efficacy.
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