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| http://dx.doi.org/10.1097/CM9.0000000000000534 | DOI Listing |
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Nursing knowledge in cardio-oncology: results of an international learning needs-assessment survey.
Cardiooncology
January 2025
Dept of Oncology Tier 2 Canada Research Chair, University of Alberta, Alberta, Canada.
Background: With early detection and improvements in systemic and local therapies, millions of people are surviving cancer, but for some at a high cost. In some cancer types, cardiovascular disease now competes with recurrent cancer as the cause of death. Traditional care models, in which the cardiologist or oncologist assess patients individually, do not address complex cancer and cardiovascular needs.
View Article and Find Full Text PDFCorticocortical (CC) projections in the visual system facilitate hierarchical processing of sensory information. In addition to direct CC connections, indirect cortico-thalamo-cortical (CTC) pathways through the pulvinar nucleus of the thalamus can relay sensory signals and mediate cortical interactions according to behavioral demands. While the pulvinar connects extensively to the entire visual cortex, it is unknown whether transthalamic pathways link all cortical areas or whether they follow systematic organizational rules.
View Article and Find Full Text PDFOptimizing a mobile just-in-time adaptive intervention (JITAI) for weight loss in young adults: Rationale and design of the AGILE factorial randomized trial.
Contemp Clin Trials
January 2025
Department of Nutrition, Gillings School of Global Public Health and School of Medicine, University of North Carolina at Chapel Hill, 135 Dauer Drive, 245 Rosenau Hall, CB # 7461, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, 450 West Drive, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, 135 Dauer Drive, 170 Rosenau Hall, CB #7400, Chapel Hill, NC 27599, USA; Nutrition Research Institute, North Carolina Research Campus, 500 Laureate Way, Kannapolis, NC 28081, USA.
Background: Young adults (YAs) are underrepresented in behavioral health and weight loss interventions and express interest in flexible, highly tailored programs. Mobile interventions are a lower-burden, scalable approach to providing behavioral support. Just-in-time-adaptive interventions (JITAI) promise to deliver the "right" support at the "right" time using real-time data from smartphones and sensors.
View Article and Find Full Text PDFEffect of molecular weight of tyramine-modified hyaluronan on polarization state of THP-1 and peripheral blood mononuclear cells-derived macrophages.
Biomater Adv
December 2024
AO Research Institute Davos, Clavadelerstrasse 8, Davos 7270, Switzerland.
The immunomodulatory properties of hyaluronan and its derivatives are key to their use in medicine and tissue engineering. In this work we evaluated the capability of soluble tyramine-modified hyaluronan (THA) synthesized from hyaluronan of two molecular weights (low M = 280 kDa and high M = 1640 kDa) for polarization of THP-1 and peripheral blood mononuclear cells (PBMCs)-derived macrophages (MΦs). We demonstrate the polarization effects of the supplemented THA by flow cytometry and bead-based multiplex immunoassay for the THP-1 derived MΦs and by semi-automated image analysis from confocal microscopy, immunofluorescent staining utilizing CD68 and CD206 surface markers, RT-qPCR gene expression analysis, as well as using the enzyme-linked immunosorbent assay (ELISA) for PBMCs-derived MΦs.
View Article and Find Full Text PDFTicks jump in a warmer world: Global distribution shifts of main pathogenic ticks are associated with future climate change.
J Environ Manage
January 2025
College of Life Sciences, Shaanxi Normal University, Xi'an, 710119, China.
In recent decades, the threats of ticks and tick-borne diseases (TBDs) increased extensively with environmental change, urbanization, and rapidly changing interactions between human and animals. However, large-scale distribution of tick and TBD risks as well as their relationship with environmental change remain inadequately unclear. Here, we first proposed a "tick-pathogen-habitat-human" model to project the global potential distribution of main pathogenic ticks using a total of 70,714 occurrence records.
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