AI Article Synopsis
- A 22-year-old woman was hospitalized due to severe headache and confusion that impaired her consciousness.
- Initial tests ruled out common neurological conditions, but her symptoms persisted and varied over weeks.
- Treatment with sodium valproate and topiramate improved her headaches and mental state, suggesting a unique form of migraine called confusional migraine that might need more research in adults.
Article Abstract
A 22-year-old female was admitted to our hospital due to acute onset of severe headache, confusion, and deterioration of consciousness. Results of initial examinations did not suggest cerebrovascular diseases, encephalitis, or nonconvulsive status epilepticus. Over the next several weeks, her level of consciousness fluctuated in parallel with the severity of headache. The electroencephalogram, recorded during a symptomatic episode, showed lack of posterior dominant rhythm, and the single-photon emission CT (SPECT) also revealed a decrease in cerebral blood flow predominantly in the occipital lobes. Administration of sodium valproate and topiramate, recommended as treatment for migraine, dramatically ameliorated her headache and consciousness. Although this was an adult-onset case, her symptoms and clinical course were similar with the diagnosis of ICHD-3-unlisted confusional migraine rather than other listed subtypes of migraine with aura. Further accumulation of similar adult-onset cases is necessary to clarify the nature of this illness.
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| http://dx.doi.org/10.5692/clinicalneurol.cn-001337 | DOI Listing |
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