Background: For many years standards of medical care for newborns have been created and perfected with the goal of improving care, including early detection of congenital defects.
Objectives: The objective of the study was to assess the circulatory system in newborns born at basic level of perinatal care centers and the comparison of specific parameters of cardiac function and structure according to the method of birth, body mass, sex, Apgar score, pulse oximetry results, and presence of other pathologies.
Material And Methods: The study was carried out in 255 newborns aged 3-14 days. The children were assessed according to Apgar score, were weighed and pulse oximetry testing was carried out, and symptoms of neonatal jaundice or infection were taken into account. Each child was subjected to a physical examination and echocardiographic examination.
Results: Among the group studied, 3.5% of children had defects of the circulatory system and functional disorders.
Conclusions: Pulse oximetry testing, due to its low level of invasiveness, high sensitivity and specificity, low cost and repeatability, should be used as the primary screening test, allowing for early detection of critical congenital heart defects (CHDs). It should be stressed that the test should be repeated before discharge of newborns from the neonatology department so as to avoid missing CHDs which are asymptomatic or mute at birth. Morphological and functional assessment of specific structures of the heart in delivered newborns showed correlation of the size of the left ventricle (LV) with body mass. The remaining factors, such as method of delivery, sex, neonatal jaundice, and audible murmur, were irrelevant. Routine cardiological assessment of healthy newborns is therefore not necessary.
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http://dx.doi.org/10.17219/acem/110327 | DOI Listing |
Circ Cardiovasc Interv
January 2025
Division of Cardiology, Department of Medicine, University of Washington Medical Center, Seattle (E.J.S., T. Salahuddin, J.A.D.).
Background: Intravascular imaging (IVI) is widely recognized to improve outcomes after percutaneous coronary intervention (PCI). However, IVI is underutilized and is not yet established as a performance measure for quality PCI.
Methods: We examined temporal trends of IVI use for all PCIs performed at Veterans Affairs hospitals in the United States from 2010 to 2022 using retrospective observational cohorts.
Circ Arrhythm Electrophysiol
January 2025
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.H., M.E.R., O.Y., G.N.K., N.O., T.K., L.N., D.L.P., K.C.S.).
Background: Power-controlled radiofrequency ablation with irrigated-tip catheters has been the norm for ventricular ablation for almost 2 decades. New catheter technology has recently integrated more accurate tissue temperature sensing enabling temperature-controlled irrigated ablation. We aimed to investigate the in vivo ablation parameters and lesion formation characteristics in ventricular myocardium using a novel temperature-controlled radiofrequency catheter.
View Article and Find Full Text PDFColomb Med (Cali)
January 2025
Karabuk University Faculty of Medicine, Department of Cardiology, Karabuk, Turkey Karabük University Karabuk University Faculty of Medicine Department of Cardiology Karabuk Turkey.
Background: The association of fragmented QRS (fQRS) with many cardiac pathologies such as cardiac fibrosis has been described previously. Paraaortic adipose tissue (PAT) is thought to be associated with many cardiac diseases and there is only one publication on its echocardiographic evaluation.
Aims: To describe the possible relationship between fQRS and PAT.
Front Immunol
January 2025
Department of General Surgery, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Background: Adenocarcinoma of the esophagogastric junction (AEGJ) is a highly aggressive tumor that frequently metastasizes to the liver. Understanding the cellular and molecular mechanisms that drive this process is essential for developing effective therapies.
Methods: We employed single-cell RNA sequencing to analyze the tumor heterogeneity and microenvironmental landscape in patients with AEGJ liver metastases.
Indian Dermatol Online J
December 2024
Department of Dermatology, Venereology, and Leprosy, GSL Medical College and General Hospital, Rajahmahendravaram, Andhra Pradesh, India.
Background: Chronic spontaneous urticaria (CSU) appears to share some pathomechanisms with metabolic syndrome (MS), such as proinflammatory state, increased oxidative stress, changes in adipokine profile, and coagulation system activation.
Aim And Objectives: To evaluate clinical and laboratory parameters of MS in CSU patients and to assess relationship of MS with duration and severity of CSU, Ig-E, thyroid-stimulating hormone (TSH), C-reactive protein (CRP), and autologous serum skin test (ASST).
Materials And Methods: A hospital-based cross-sectional study was conducted on 131 CSU cases and 131 controls who were age- and sex-matched.
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