AI Article Synopsis

  • The study examined the health profiles of preterm infants born to mothers with urinary tract infections (UTI) and those with hypertensive disorders (HD).
  • It involved 59 mothers, narrowing down to 12 UTI and 18 HD participants, with assessments made at birth and 6 months of corrected age.
  • Findings revealed higher plasma triglyceride levels in infants of HD-mothers, indicating that maternal hypertension can influence metabolic health early in development.

Article Abstract

Objective: The present study evaluated the anthropometric and metabolic profiles of preterm infants (PT) born from mothers with urinary tract infections (UTI) and mothers with hypertensive disorders (HD).

Method: This was a longitudinal prospective study conducted between May 2015 and August 2016. First, 59 mothers with premature birth were included; after excluding 29 mothers, two subgroups were created: UTI-mothers (n=12) and HD-mothers (n=18). The anthropometric and metabolic variables of mothers and their respective PT were analyzed at birth and at 6 months of corrected age (CA).

Results: Plasma triglyceride levels were higher among HD-mothers and their respective PT in comparison with UTI-mothers and their PT at 6 m of CA.

Conclusion: Plasma triglyceride level is an important metabolic biomarker in HD-mothers resulting in higher triglyceride levels among PT at the CA of 6 m, suggesting an early programming effect of maternal hypertension.

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Source
http://dx.doi.org/10.1590/0034-7167-2017-0179DOI Listing

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