Neutrophil-to-lymphocyte ratio in ocular diseases: a systematic review.

Int J Ophthalmol

Department of Ophthalmology, Ufuk University Faculty of Medicine, Ankara 06830, Turkey.

Published: December 2019

AI Article Synopsis

  • The study aimed to summarize findings on the neutrophil-to-lymphocyte ratio (NLR) and its association with ocular diseases.
  • A comprehensive search yielded 4473 publications; 75 were relevant to ocular diseases, primarily from clinics in Turkey, with a trend of increasing publications over time.
  • Elevated NLR is suggested as a cost-effective and accessible marker for diagnosing and predicting outcomes in ocular diseases.

Article Abstract

Aim: To summarize the results of studies investigating neutrophil-to-lymphocyte ratio (NLR) and to identify the role of NLR in ocular diseases.

Methods: With the aim of identifying the studies related to NLR, a search was conducted on http://www.ncbi.nlm.nih.gov/pubmed by utilizing the key words "neutrophil lymphocyte ratio, ocular diseases, and eye diseases" up to February 2018. All of the original articles were assessed according to date of publications, countries, clinics and topics. Studies about ocular inflammatory diseases were evaluated according to their qualifications, review methods and results.

Results: A total of 4473 publications, including original research articles and reviews were screened. The number of publications was shown a regular logarithmic increase over the years. The majority of studies were performed by clinics in Turkey and many of these publications were performed by oncology and cardiology clinics. A total of 75 publications were identified to be about ocular diseases.

Conclusion: Elevated NLR as a cheap, reproducible, and readily available marker could be used as a diagnostic and/or prognostic marker in ocular diseases.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901879PMC
http://dx.doi.org/10.18240/ijo.2019.12.18DOI Listing

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