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Maslinic acid improves mitochondrial function and inhibits oxidative stress and autophagy in human gastric smooth muscle cells.
Open Life Sci
January 2025
Department of Pediatrics, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, No. 134 Dong Street, Fuzhou, Fujian, 350001, China.
Functional dyspepsia (FD) is a chronic disease that occurs in the gastroduodenal region and significantly impacts human health. Maslinic acid (MA), a pentacyclic triterpene acid, is the primary bioactive ingredient in Chinese medicinal herbs such as hawthorn, which exhibits beneficial impacts on the regulation of various disease progressions. However, the specific functions and associated pathways of MA in FD progression remain unclear and require further investigation.
View Article and Find Full Text PDFA Standardized Classification Scheme for Gastroduodenal Disorder Evaluation Using the Gastric Alimetry System: Prospective Cohort Study.
Gastro Hep Adv
September 2024
Department of Surgery, The University of Auckland, Auckland, New Zealand.
Background And Aims: Gastric Alimetry™ (Alimetry, New Zealand) is a new clinical test for gastroduodenal disorders involving simultaneous body surface gastric electrical mapping and validated symptom profiling. Studies have demonstrated a range of distinct pathophysiological profiles, and a classification scheme is now required. We used Gastric Alimetry spectral and symptom profiles to develop a mechanism-based test classification scheme, then assessed correlations with symptom severity, psychometrics, and quality of life.
View Article and Find Full Text PDFGastroduodenal Obstruction Due to Bouveret's Syndrome: A Case Report.
Cureus
December 2024
Surgery, Hospital General Tacuba, Institute for Social Security and Services for State Workers (ISSSTE), Mexico City, MEX.
Bouveret's syndrome is a rare disorder that causes upper gastrointestinal obstruction, typically in elderly patients with a history of chronic cholelithiasis. We present an unusual case of a 58-year-old woman with untreated vesicular lithiasis who developed Bouveret's syndrome. She presented with severe abdominal pain, nausea, vomiting, and abdominal distension.
View Article and Find Full Text PDFSUCCESSFUL EMERGENCY ARTERIAL EMBOLIZATION FOR MASSIVE GASTRODUODENAL BLEEDING IN HIGH-RISK PATIENT. CASE REPORT.
Georgian Med News
September 2024
2A. Tsereteli State University, Faculty of Medicine, Kutaisi, Georgia.
Massive upper gastrointestinal bleeding still remains a challenge, which can cause serious clinical problems especially in high-risk patients. We present a rare case of patient with complex pathology successfully managed by endovascular treatment. A 78-year-old man with a medical history of chronic bronchitis, several minor strokes, type II diabetes, a 30-year history of smoking, and a family history of cardiovascular disease, presented with severe pain on the left side of his chest radiating to his left arm.
View Article and Find Full Text PDFModification of the modified Graham patch repair for duodenal perforation using the gastrocolic ligament: Two case reports.
Int J Surg Case Rep
December 2024
Department of Surgery, St. Joseph's University Medical Center, Paterson, NJ, United States of America.
Introduction: Gastroduodenal perforations are relatively common surgical emergencies with mortality rates as high as 40%. The Graham patch repair is one surgical approach but may need to be modified when the patient lacks viable omentum. The gastrocolic ligament can be utilized to repair these perforations for coverage.
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