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Backgrounds: Scrub Typhus is a re-emerging illness with considerable morbidity and mortality and affected children have nonspecific sign symptoms. This study was conducted to find out the risk factors, clinical characteristics and laboratory profile and treatment outcome of scrub typhus among the children admitted in tertiary level pediatric hospital for febrile illness.
Methods: A case control study was conducted among hospitalized children with acute febrile illness in a government pediatric referral hospital of central Nepal for two years (2021 to Sept 2023), who were tested using Scrub Typhus Antibody Rapid Test Kit.
Diagnostic Dilemma between Scrub Typhus Meningoencephalitis and Dengue Encephalopathy Resolved! - A Novel Prediction Score.
Neurol India
September 2024
Department of Pediatrics, King George's Medical University, Lucknow, Uttar Pradesh, India.
Article Synopsis
- Scrub typhus and dengue cause similar symptoms in acute encephalitis but require different treatment approaches.
- A study involving 204 children aimed to develop a scoring system to effectively distinguish between scrub typhus meningoencephalitis (STM) and dengue encephalopathy (DE).
- The resulting score showed high accuracy, with 100% specificity and predictive value, aiding physicians in diagnosing and managing these infections properly.
Clinico-Laboratory Profile of Hypertriglyceridemia Thalassemia Syndrome: A Case Series in a Paediatric Tertiary Care Centre.
Cureus
August 2024
Paediatric Medicine, Dr B C Roy Post Graduate Institute of Paediatric Sciences, Kolkata, IND.
Background: Increased hemolysis and repeated blood transfusion trigger oxidative stress resulting in numerous adverse effects in beta-thalassemia patients. Extreme elevation of triglyceride level is a rare clinical entity seen in these patients. It is presumed to be caused due to an increase in oxidative stress and is termed Hypertriglyceridemia Thalassemia Syndrome.
View Article and Find Full Text PDFPrevalence, clinico-laboratory features, and the functional outcome of children with scrub typhus meningoencephalitis-a cohort study.
J Trop Pediatr
August 2022
Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry 605006, India.
Scrub typhus is being reported as the most common cause of childhood meningoencephalitis (ME) in India. Hence, we planned to estimate the proportion of scrub typhus infection among children aged 1 month to 12 years with the clinical diagnosis of ME and to evaluate their demographic, clinical and laboratory characteristics. This cohort study was conducted in the Department of Pediatrics of a tertiary care teaching hospital in south India.
View Article and Find Full Text PDFTriaging of COVID-19 patients using low dose chest CT: Incidence and factor analysis of lung involvement on CT images.
J Infect Chemother
June 2022
Department of Diagnostic Radiology, Graduate School of Biomedical and Health Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan. Electronic address:
Article Synopsis
- - The study aimed to explore how often lung involvement appears in COVID-19 patients using CT scans and to identify factors that could help decide when to use CT imaging for patient triage.
- - Out of 192 patients, 62.5% showed lung involvement on CT, with age, albumin levels, lactate dehydrogenase, and C-reactive protein being significant predictors in the final model.
- - The developed prediction model showed promise with a ROC curve area of 0.83, indicating its potential to aid in determining which COVID-19 patients should undergo CT scans based on their clinical data.
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