AI Article Synopsis
- Phthalocyanines are promising photosensitisers for photodynamic therapy due to their excellent photoproperties.
- Various derivatives are currently undergoing clinical trials, focusing on enhancing their effectiveness in treating cancer.
- Researchers are developing advanced phthalocyanines with optimized properties, dual actions, and targeted activation to improve therapeutic outcomes.
Article Abstract
Phthalocyanines exhibit superior photoproperties that make them a surely attractive class of photosensitisers for photodynamic therapy of cancer. Several derivatives are at various phases of clinical trials, and efforts have been put continuously to improve their photodynamic efficacy. To this end, various strategies have been applied to develop advanced phthalocyanines with optimised photoproperties, dual therapeutic actions, tumour-targeting properties and/or specific activation at tumour sites. The advantageous properties and potential of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer are highlighted in this tutorial review.
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| http://dx.doi.org/10.1039/c9cs00129h | DOI Listing |
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