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In underwater diving, decompression schedules are based on compartmental models of nitrogen and helium tissue kinetics. However, these models are not based on direct measurements of nitrogen and helium kinetics. In isoflurane-anesthetized sheep, nitrogen and helium kinetics in the hind limb (n = 5) and brain (n = 5) were determined during helium-oxygen breathing and after return to nitrogen-oxygen breathing.

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Recent advances in submarine rescue systems have allowed a transfer under pressure of crew members being rescued from a disabled submarine. The choice of a safe decompression procedure for pressurised rescuees has been previously discussed, but no schedule has been validated when the internal submarine pressure is significantly increased i.e.

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Technical divers perform deep, mixed-gas 'bounce' dives, which are inherently inefficient because even a short duration at the target depth results in lengthy decompression. Technical divers use decompression schedules generated from modified versions of decompression algorithms originally developed for other types of diving. Many modifications ostensibly produce shorter and/or safer decompression, but have generally been driven by anecdote.

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Scope and design of the GUSI international research program.

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Changes in total lung resistance (RL) during inhalation of cold gas mixtures were measured in 4 human volunteers during an experimental dive at 46 ATA. The subjects breathed helium-nitrogen-oxygen mixtures during the decompression schedule, and measurements were performed at 46, 36, 21, 12.5, 6 and 2 ATA (1 ATA = 100 kPa).

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