MicroRNAs (miRNAs) are a class of short noncoding RNAs that play critical roles in the regulation of a broad range of biological processes. Like transcription factors, miRNAs exert their effects by modulating the expression of networks of genes that operate in common or convergent pathways. CD8 T cells are critical agents of the adaptive immune system that provide protection from infection and cancer. Here, we review the important roles of miRNAs in the regulation of CD8 T cell biology and provide perspectives on the broader emerging principles of miRNA function.
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| http://dx.doi.org/10.21037/ncri.2019.07.02 | DOI Listing |
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