Celiac Antigenicity of Ancient Wheat Species.

Foods

Department of Plant Sciences, North Dakota State University, Fargo, ND 58108-6050, USA.

Published: December 2019

AI Article Synopsis

  • Ancient grains like einkorn, emmer, and Kamut are being studied for their nutritional value and potential impact on celiac disease.
  • A mass spectrometric method was used to identify celiac epitopes in these grains, and reverse phase-HPLC helped analyze their gliadin protein profiles.
  • Findings indicate that these grains contain celiac epitopes and have distinct gliadin compositions, which may affect their functionality in food products.

Article Abstract

Ancient grains have gained renewed interest in the last few years due to their perceived nutritional benefits. The goal of this study was to examine the presence of celiac epitopes in different ancient grains and determine differences in the gliadin protein profile of such grains. To investigate celiac epitopes, an untargeted mass spectrometric method was used, and the gliadin protein profile was studied using reverse phase-HPLC. Our findings show that celiac epitopes can be detected in wheat-related ancient grains, such as einkorn, emmer, and Kamut, indicating that these ancient grains have the potential to elicit the immune response associated with celiac disease. Additionally, the results showed that the gliadin protein composition is significantly different between ancient grain species, which could result in varying functional properties in end-use applications.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963764PMC
http://dx.doi.org/10.3390/foods8120675DOI Listing

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