Behavioral adaptation refers to the change in road user behavior in response to new conditions (Kulmala & Rämä, 2013). Behavioral adaptation can improve safety, but it can also reduce or even eliminate anticipated safety benefits of many well-intentioned road safety countermeasures. To expect driver behavior to remain the same after the implementation of a change in the road, vehicle, or driving environment, is naïve. Empirical studies that do not consider the full range of behavior affected by a countermeasure may similarly overlook the consequences of behavioral adaptation. This paper considers a number of examples of driver safety countermeasure implementation where unexpected results occurred and behavioral adaptation was the likely culprit. These examples are drawn from highway design, traffic control device design, vehicle countermeasures, enforcement countermeasures, driver education countermeasures and impaired driving policies. A previously presented inventory of characteristics to consider when estimating the likelihood for behavioral adaptation (Rudin-Brown et al., 2013) is expanded and presented within the context of the Qualitative Model of Behavioral Adaptation (Rudin-Brown & Noy, 2002; Rudin-Brown, 2010), in the hopes of addressing the question "When can we anticipate the safety effect of a treatment, and when not?"
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http://dx.doi.org/10.1016/j.aap.2019.105370 | DOI Listing |
Invest Radiol
January 2025
From the Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (A. Schwarz, A. Simon, A.M.); Siemens Healthineers AG, Forchheim, Germany (A. Schwarz, C.H., J.D., A. Simon); Institute for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany (F.K.W., S.G., M.S.); and Institut for Radiology, Pediatric and Neuroradiology, Helios Hospital, Schwerin, Germany (H.-J.R.).
Objective: Respiratory motion can affect image quality and thus affect the diagnostic accuracy of CT images by masking or mimicking relevant lung pathologies. CT examinations are often performed during deep inspiration and breath-hold to achieve optimal image quality. However, this can be challenging for certain patient groups, such as children, the elderly, or sedated patients.
View Article and Find Full Text PDFScience
January 2025
Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
Single-cell decisions made in complex environments underlie many bacterial phenomena. Image-based transcriptomics approaches offer an avenue to study such behaviors, yet these approaches have been hindered by the massive density of bacterial messenger RNA. To overcome this challenge, we combined 1000-fold volumetric expansion with multiplexed error-robust fluorescence in situ hybridization (MERFISH) to create bacterial-MERFISH.
View Article and Find Full Text PDFPLoS Biol
January 2025
Carney Institute for Brain Science, Department of Cognitive & Psychological Sciences, Brown University, Providence, Rhode Island, United States of America.
The basal ganglia (BG) play a key role in decision-making, preventing impulsive actions in some contexts while facilitating fast adaptations in others. The specific contributions of different BG structures to this nuanced behavior remain unclear, particularly under varying situations of noisy and conflicting information that necessitate ongoing adjustments in the balance between speed and accuracy. Theoretical accounts suggest that dynamic regulation of the amount of evidence required to commit to a decision (a dynamic "decision boundary") may be necessary to meet these competing demands.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Ernst Strüngmann Institute, Frankfurt am Main 60528, Germany.
The dynamics of neuronal systems are characterized by hallmark features such as oscillations and synchrony. However, it has remained unclear whether these characteristics are epiphenomena or are exploited for computation. Due to the challenge of selectively interfering with oscillatory network dynamics in neuronal systems, we simulated recurrent networks of damped harmonic oscillators in which oscillatory activity is enforced in each node, a choice well supported by experimental findings.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Experimental Physics V, Department of Physics, University of Bayreuth, D-95447 Bayreuth, Germany.
Photosynthetic microbes have evolved and successfully adapted to the ever-changing environmental conditions in complex microhabitats throughout almost all ecosystems on Earth. In the absence of light, they can sustain their biological functionalities through aerobic respiration, and even in anoxic conditions through anaerobic metabolic activity. For a suspension of photosynthetic microbes in an anaerobic environment, individual cellular motility is directly controlled by its photosynthetic activity, i.
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