AI Article Synopsis

  • People with diabetes face a higher risk of serious heart and brain issues after acute coronary syndrome, but there aren't effective prediction tools for their follow-up care.
  • This study analyzed data from 1400 patients to develop the PG-HACKER score, which assesses various risk factors to predict adverse events.
  • The PG-HACKER score is a user-friendly and accessible tool that helps doctors and patients identify the risk of major cardiac and cerebrovascular events after an acute coronary syndrome episode.*

Article Abstract

Background And Objectives: The risk of major adverse cardiac and cerebrovascular events following acute coronary syndrome is increased in people with diabetes. Predicting out-of-hospital outcomes upon follow-up remains difficult, and no simple, well-validated tools exist for this population at present. We aim to evaluate several factors in a competing risks model for actionable evaluation of the incidence of major adverse cardiac and cerebrovascular events in diabetic outpatients following acute coronary syndrome.

Methods: Retrospective analysis of consecutive patients admitted for acute coronary syndrome in two centres. A Fine-Gray competing risks model was adjusted to predict major adverse cardiac and cerebrovascular events and all-cause mortality. A point-based score is presented that is based on this model.

Results: Out of the 1400 patients, there were 783 (55.9%) with at least one major adverse cardiac and cerebrovascular event (417 deaths). Of them, 143 deaths were due to non-major adverse cardiac and cerebrovascular events. Predictive Fine-Gray models show that the 'PG-HACKER' risk factors (gender, age, peripheral arterial disease, left ventricle function, previous congestive heart failure, Killip class and optimal medical therapy) were associated to major adverse cardiac and cerebrovascular events.

Conclusion: The PG-HACKER score is a simple and effective tool that is freely available and easily accessible to physicians and patients. The PG-HACKER score can predict major adverse cardiac and cerebrovascular events following acute coronary syndrome in patients with diabetes.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510367PMC
http://dx.doi.org/10.1177/1479164119892137DOI Listing

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