AI Article Synopsis
- Glial astrocytes play a crucial role in the development and functioning of the nervous system across both vertebrates and invertebrates.
- Research indicates that these cells have circadian clocks that contribute to the regulation of behaviors like sleep and daily rhythms.
- Recent studies focus on fruit flies and mice to explore how astrocytes and their internal clocks influence rhythmic behavior.
Article Abstract
Glial astrocytes of vertebrates and invertebrates are important modulators of nervous system development, physiology, and behavior. In all species examined, astrocytes of the adult brain contain conserved circadian clocks, and multiple studies have shown that these glial cells participate in the regulation of circadian behavior and sleep. This short review summarizes recent work, using fruit fly (Drosophila) and mouse models, that document participation of astrocytes and their endogenous circadian clocks in the control of rhythmic behavior. This article is categorized under: Gene Expression and Transcriptional Hierarchies > Regulatory Mechanisms Nervous System Development > Flies.
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| http://dx.doi.org/10.1002/wdev.372 | DOI Listing |
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