Foot ulcers, infections, and deformity are some of the major sources of mortality and morbidity among the diabetic population. The relationship between glycated hemoglobin (HbA1c) and diabetic peripheral neuropathy (DPN) has been well established. There is a dearth of literature on the relationship between vibration perception threshold (VPT) and HbA1c values. So, the objective of the study was to determine the strength of linear relationship between HbA1c levels and vibration perception threshold in DPN. This cross-sectional study was conducted at Kasturba Hospital, Manipal, and diabetic foot screening camps held at various parts of Udupi district. Ethical approval was obtained from the Institutional Ethics Committee, Kasturba Hospital, Manipal (IEC:281/2017). A total of 534 participants ranging from 30 to 70 years of age and were diagnosed with type 2 diabetes mellitus on medications were included in the study. Neuropathy assessment consisting of monofilament and vibration perception threshold was done using Neurotouch beta version (Yostra Labs, Bengaluru, India). HbA1c measurement was done using turbidimetric inhibition immunoassay technique (Roche Diagnostics, Mannheim, Germany). Pearson correlation coefficient showed a moderate to good correlation between HbA1c and VPT ( = .0.753, < .001). Linear regression result has shown a significant relationship of VPT with HbA1c (4.033 [95% confidence interval = 3.67-4.39]). The present study has concluded that there is strong relationship between HbA1c values and VPT and could be a predictor for complications in the foot following DPN.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1177/1534734619882173 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparison of Conventional Syringe with Camouflaged Syringe and Vibration-assisted Syringe for Pain and Fear Perception during Local Anesthetic Administration in Children: A Split-mouth Randomized Controlled Trial.
Int J Clin Pediatr Dent
November 2024
Department of Pediatric and Preventive Dentistry, Dr Ziauddin Ahmad Dental College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
Aim And Background: Although local anesthesia (LA) eliminates pain and instills a positive dental attitude, the physical appearance of its syringe is highly fear provoking and often intolerable. Therefore, the purpose of this study was to evaluate the pain and fear perception in camouflaged syringe (CS) and vibration-assisted syringe (VA) when compared with conventional syringe and with each other (VACS) during local anesthetic administration in pediatric patients aged between 6 and 12 years.
Materials And Methods: Eighty-five subjects were randomly assigned into three groups: CS group ( = 7), VA group ( = 26), and VACS group ( = 27).
Individual differences elucidate the perceptual benefits associated with robust temporal fine-structure processing.
Proc Natl Acad Sci U S A
January 2025
Department of Communication Science and Disorders, University of Pittsburgh, Pittsburgh, PA 15213.
Article Synopsis
- The auditory system can precisely track quick changes in sound, but the importance of this ability (temporal fine structure or TFS) for hearing is still debated.
- Researchers studied 200 participants to see how TFS sensitivity affects speech perception in noisy environments.
- Results showed that better TFS sensitivity helped more with listening in reverberant spaces and led to quicker responses, suggesting it plays a key role in everyday hearing experiences.
Multimaterial cryogenic printing of three-dimensional soft hydrogel machines.
Nat Commun
January 2025
Robotics Institute and State Key Laboratory of Mechanical System and Vibration, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Hydrogel-based soft machines are promising in diverse applications, such as biomedical electronics and soft robotics. However, current fabrication techniques generally struggle to construct multimaterial three-dimensional hydrogel architectures for soft machines and robots, owing to the inherent hydrogel softness from the low-density polymer network nature. Herein, we present a multimaterial cryogenic printing (MCP) technique that can fabricate sophisticated soft hydrogel machines with accurate yet complex architectures and robust multimaterial interfaces.
View Article and Find Full Text PDFHow to determine hands' vibration perception thresholds - a systematic review.
Behav Res Methods
December 2024
Algoritmi Research Centre, University of Minho, Campus de Azurém, 4800-058, Guimarães, Portugal.
The vibration perception threshold (VPT) is the minimum amplitude required for conscious vibration perception. VPT assessments are essential in medical diagnostics, safety, and human-machine interaction technologies. However, factors like age, health conditions, and external variables affect VPTs.
View Article and Find Full Text PDFBiomimetic Strategies of Slip Sensing, Perception, and Protection in Prosthetic Hand Grasp.
Biomimetics (Basel)
December 2024
School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China.
This study develops biomimetic strategies for slip prevention in prosthetic hand grasps. The biomimetic system is driven by a novel slip sensor, followed by slip perception and preventive control. Here, we show that biologically inspired sensorimotor pathways can be restored between the prosthetic hand and users.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!