Otosclerosis is a bone remodeling disorder affecting exclusively the human temporal bone which causes small bony lesions in the otic capsule. The symptoms depend on the location and the extent of the otosclerotic foci. Hence, clinically the most relevant sign is the conductive hearing loss due to the stapedial otosclerosis with fixation of the stapes footplate. In many cases, the specific anamnestic features, the age of presentation and usually the absence of tympanic membrane pathology can provide a strong clinical suspicion for otosclerosis. Although audiometric and imaging examinations and VEMP testing can confirm our preoperative diagnosis, the histolopathologic examination of the removed stapes footplate is the most accurate way to determine the diagnosis. Orv Hetil. 2019; 160(51): 2007-2011.
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http://dx.doi.org/10.1556/650.2019.31583 | DOI Listing |
Eur Ann Otorhinolaryngol Head Neck Dis
December 2024
Service d'ORL et de chirurgie cervico-faciale, centre hospitalo-universitaire, Dijon, France; Laboratoire ICMUB, UMR CNRS 6302, université de Bourgogne, Dijon, France.
Aim: To evaluate the audiometric results of tympanoplasty with stapedectomy and insertion of a synthetic total ossicular replacement prosthesis (TORP).
Material And Methods: Retrospective observational study conducted on a cohort of 15 patients (16 ears) aged 10 to 58 years (mean: 36 years) with chronic otitis media (COM) and tympanosclerosis (n=9), stapediovestibular ankylosis (n=3), minor aplasia (n=3) or post-traumatic ossicular dislocation (n=1). Treatment consisted in tympanoplasty with stapedectomy and TORP placement by the same operator, between December 1, 2012 and January 30, 2023, in a French university hospital department, with follow-up ranging from 2 to 92 months (mean: 24 months).
Indian J Otolaryngol Head Neck Surg
December 2024
Patiala, Punjab 147001 India.
AJNR Am J Neuroradiol
November 2024
From the Department of Radiology (Shaojie Chang, John C. Benson, John I. Lane, Michael R Bruesewitz, Joseph R Swicklik, Jamison E. Thorne, Emily K. Koons, Cynthia H. McCollough, Shuai Leng) and Department of Otolaryngology-Head and Neck Surgery (Matthew L. Carlson), Mayo Clinic, Rochester, MN, 55905, USA.
Background And Purpose: Ultra-high-resolution (UHR) photon-counting-detector (PCD) CT improves image resolution but increases noise, necessitating use of smoother reconstruction kernels that reduce resolution below the system's 0.110 mm maximum spatial resolution. To address this, a denoising convolutional neural network (CNN) was developed to reduce noise in images reconstructed with the available sharpest reconstruction kernel while preserving resolution for enhanced temporal bone visualization.
View Article and Find Full Text PDFBackground: To create and develop a delivery approach for clinical inner ear gene therapy, we conducted a study of trans-round window membrane (RWM) microinjection using a pipetting microneedle via transcanal endoscopic ear surgery (TEES).
Methods: The implementation of the trans-RWM microinjection surgery involved seven cadaveric specimens, and the surgical procedures and the pipetting microneedle were developed and optimized. The TEES procedures included tympanic cavity visualization, RWM exposure, stapes footplate perforation, and trans-RWM microinjection.
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