Sole ulcers negatively affect production and animal welfare in dairy cows. Hoof trimming around drying off is frequently recommended, but has not previously been evaluated scientifically. The association between hoof trimming around drying off and the odds of sole ulcers in the following lactation was evaluated based on recordings from 621,228 hoof trimmings in Danish dairy herds. Overall, 6.2% of cows had sole ulcers at the first hoof trimming 0-180 days in milk. The odds of sole ulcers increased with increasing days in milk, and were approximately 20% lower in cows hoof trimmed around drying off. Odds were higher in older cows, and in cows with sole ulcers in the previously lactation. Hoof trimming around drying off may help reduce the occurrence of sole ulcers in the following lactation.
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http://dx.doi.org/10.1016/j.tvjl.2019.105408 | DOI Listing |
Nurse Educ Pract
January 2025
Dokuz Eylül University Health Science Institute, Izmir 35340, Turkey. Electronic address:
Aim: The study compares knowledge, skills, anxiety, satisfaction and self-confidence regarding suctioning between students trained using a partial task trainer with moulage and those using a low-fidelity simulator.
Background: Moulage application in simulation has been used in nursing skills training, such as intravenous therapy, pressure ulcer and burn care, but not for suctioning.
Design: A randomized controlled study with pre-test, post-test design.
Crit Care Resusc
December 2024
Department of Intensive Care, Alfred Health, 55 Commercial Road, Melbourne, 3181, VIC, Australia.
Objective: To describe the epidemiology and clinical features of pressure injury (PI) development in adult patients supported with extracorporeal membrane oxygenation (ECMO).
Design: Retrospective, observational, cohort study from January 2018 to May 2023.
Setting: A single-centre high-volume ECMO specialist intensive care unit (ICU).
World J Gastroenterol
December 2024
Division of Gastroenterology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju 26426, South Korea.
Background: For the treatment of gastritis, rebamipide, a mucoprotective agent, and nizatidine, a gastric acid suppressant, are commonly employed individually.
Aim: To compare the efficacy of Mucotra SR (rebamipide 150 mg) and Axid (nizatidine 150 mg) combination therapy with the sole administration of Axid in managing erosive gastritis.
Methods: A total of 260 patients diagnosed with endoscopically confirmed erosive gastritis were enrolled in this open-label, multicenter, randomized, phase 4 clinical trial, allocating them into two groups: Rebamipide/nizatidine combination twice daily nizatidine twice daily for 2 weeks.
J Crohns Colitis
January 2025
Department of Drug Sciences, University of Pavia, viale Taramelli 12/14, 27100 Pavia, Italy.
Background And Aims: Given the role of Receptor for Activated C Kinase 1 (RACK1) in both immune cell activation and in the maintenance of the intestinal epithelial barrier integrity, we investigated whether it was involved in inflammatory bowel disease (IBD).
Methods: RACK1 expression was analyzed in intestinal mucosal samples of healthy and IBD patients, in mice with chemically induced colitis, and in diseased in vitro 2D and 3D coculture models by luciferase assay, reverse transcription-quantitative PCR, Western blotting, immunofluorescence, and immunohistochemistry. Based on our finding that glucocorticoid-induced leucine zipper (GILZ or tsc22d3) positively correlates with RACK1 expression in IBD patients, GILZ knockout mice and cell silencing experiments were performed.
JDS Commun
November 2024
Department of Veterinary and Animal Sciences, University of Copenhagen, DK-1870 Frederiksberg C, Denmark.
Sole ulcers negatively affect cow welfare and production economy. Previous cases of sole ulcers increase the risk of new or recurrent cases, and prevention of sole ulcers during the first lactation may therefore have a long-term effect, also in later lactations. Until now, risk factors for sole ulcers in the first lactation, associated with the period before heifers calve for the first time, have not been investigated.
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