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| http://dx.doi.org/10.1152/ajpheart.00704.2019 | DOI Listing |
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A disintegrin and metallopeptidase domain (ADAM) 12, ADAM 17 mRNA and ADAM10 protein hold potential as biomarkers for detection of early gastric cancer.
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No biomarker can effectively screen for early gastric cancer (EGC). Players in the A disintegrin and metalloproteinase (ADAM)-natural killer group 2 member D (NKG2D) receptor axis may have a role for that. As a proof-of-concept pilot study, the expression of ADAM8, ADAM9, ADAM10, ADAM12, ADAM17, and major histocompatibility complex (MHC) class I chain-related sequence A (MICA), a ligand for NKG2D, in gastric cancer was investigated in silico using The Cancer Genome Atlas (TCGA) database.
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Triple-negative breast cancer, a subtype of breast cancer, is characterized by a poor prognosis. Recent studies have shown that miRNA30b acts as an oncogene and is vital for the proliferation of malignancies across various systems. This study aimed to elucidate the impact of miRNA30b on the proliferation, migration, and invasion capabilities of breast cancer cells .
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- Breast cancer is the leading cause of cancer-related deaths among women, influenced by environmental radiation and hormonal factors, with cell motility playing a key role in its development and spread.
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Altered AP-1, RUNX and EGR chromatin dynamics drive fibrotic lung disease.
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Department of Periodontics and Oral Mucosal Diseases, The Affiliated Stomatology Hospital, Southwest Medical University, Luzhou, Sichuan, China; School of Stomatology, Southwest Medical University, Luzhou, Sichuan, China; Luzhou Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, The Affiliated Stomatology Hospital, Southwest Medical University, Luzhou, Sichuan, China; Institute of Stomatology, Southwest Medical University, Luzhou, Sichuan, China. Electronic address:
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- Periodontitis is a chronic inflammatory disease that current treatments struggle to effectively manage, prompting research to identify new biomarkers and therapeutic targets using advanced genetic analysis techniques.
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