"Tofacitinib Is a Mechanism-Based Inactivator of Cytochrome P450 3A4": Revisiting the Significance of the Epoxide Intermediate and Glutathione Trapping.

Chem Res Toxicol

Johns Hopkins Drug Discovery , Johns Hopkins University, 855 North Wolfe Street , Baltimore , Maryland 21205 , United States.

Published: February 2020

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http://dx.doi.org/10.1021/acs.chemrestox.9b00455	DOI Listing

Publication Analysis

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cytochrome p450

p450 3a4"

3a4" revisiting

revisiting significance

significance epoxide

epoxide intermediate

intermediate glutathione

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