Seven new nitrile-bearing polyacetylenes, named albanitriles A-G, were isolated from a marine sponge of the genus (Order: Poecilosclerida, Family: Mycalidae) collected near Albany, Western Australia. Structural elucidation was achieved using a combination of high-resolution mass spectrometry and ultraviolet/visible, infrared, and nuclear magnetic resonance spectroscopy. The compounds were found to possess moderate activity against when compared to a metronidazole positive control.

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http://dx.doi.org/10.1021/acs.jnatprod.9b00840DOI Listing

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