Background: In the Indian system of medicine (ISM) is one of the oldest and longest used natural herbal remedy which consist of mixture of equal parts of the Gaertn. (Family- Euphorbiaceae), Retz. (Family- Combretaceae) and Terminalia beleria [Gaertn.] Roxb. (Family- Combretaceae). Currently, is being extensively researched for its various therapeutic effects including its anti-caries, antioxidant, anti-collagenase and anti-microbial activities. This fruit extract is used in various forms in the treatment of periodontitis.
Aim: The aim of the present study was to compare the clinical and microbiological benefits of routine scaling and root planing (SRP) with adjunctive use of (Hiora GA) as local drug delivery agent in the management of periodontitis.
Materials And Methods: Thirteen patients diagnosed with chronic periodontitis were included in the present study. The control sites received SRP alone and the test sites received SRP with locally delivered (Hiora GA). The clinical parameters were evaluated at baseline, 15 days and 1 month. The plaque samples were cultured anaerobically for the keystone-periodontal pathogen , and . The Mann-Whitney U-test and Wilcoxon signed-rank tests were performed to compare the results between the test and control groups.
Results: Statistically significant improvement was observed in both groups. Intergroup comparison of prevalence of microorganisms also revealed a statistically significant difference ( = 0.0007) at 15 days and 1 month.
Conclusion: Subgingivally delivered (Hiora GA) as an adjunct to SRP in the treatment of chronic periodontitis has shown anticipative results revealing slow and constant releasing property of .
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http://dx.doi.org/10.4103/ayu.AYU_40_17 | DOI Listing |
Small Methods
January 2025
Research Institute of Frontier Science, Southwest Jiaotong University, Chengdu, 610031, P. R. China.
Commercial 3D zinc foam anodes with high deposition space and ion permeation have shown great potential in aqueous ion batteries. However, the local accumulated stress from its high-curvature surface exacerbates the Zn dendrite issue, leading to poor reversibility. Herein, we have employed zincophilic N-doped carbon@Sn composites (N-C@Sn) as nano-fillings to effectively release the local stress of high curvature surface of 3D Zn foams toward dendrite-free anode in aqueous zinc ion battery (AZIB).
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Veterinarian, DSc. Departamento de medicina e cirurgia veterinária, Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro. Seropédica, RJ, Brazil.
Epistaxis is defined as bleeding from the nasal cavity and can be related to systemic causes leading to coagulation disorders, most commonly hemoparasitosis, or to localized changes in the nasal cavity itself (e.g., intranasal neoplasms).
View Article and Find Full Text PDFUrol Case Rep
January 2025
Department of Urology, Flinders Medical Centre, Adelaide, Australia.
A 39-year-old man presented with priapism. To facilitate corporal cavernosal aspiration, a dorsal penile nerve block was performed. A dose of 2000mg lignocaine was administered, instead of the intended 200mg.
View Article and Find Full Text PDFBioact Mater
April 2025
School of Life Science, Advanced Research Institute of Multidisciplinary Science, Aerospace Center Hospital, Key Laboratory of Molecular Medicine and Biotherapy, Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering, Beijing Institute of Technology, Beijing, 100081, China.
Immune checkpoint blockade (ICB) therapy is a widely favored anti-tumor treatment, but it shows limited response to non-immunogenic "cold" tumors and suffers from drug resistance. Photodynamic therapy (PDT), as a powerful localized treatment approach, can convert a "cold tumor" into a "hot tumor" by inducing immunogenic cell death (ICD) in tumor cells, thereby enhancing tumor immunogenicity and promoting tumor immunotherapy. However, the effectiveness of PDT is largely hindered by the limited penetration depth into tumor tissues.
View Article and Find Full Text PDFIowa Orthop J
January 2025
Department of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Background: The use of intraoperative intra-articular morphine has been suggested to lower postoperative pain scores and opioid use. We sought to evaluate the effectiveness of intra-articular morphine with 0.75% ropivacaine when compared to the use of ropivacaine alone.
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