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http://dx.doi.org/10.1038/s41430-019-0538-2 | DOI Listing |
J Biomed Inform
December 2024
Institute of Computer Science, University of Tartu, 51009 Tartu, Estonia; STACC, 51009 Tartu, Estonia.
Objective: This study aims to address the gap in the literature on converting real-world Clinical Document Architecture (CDA) data into the Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM), focusing on the initial steps preceding the mapping phase. We highlight the importance of a repeatable Extract-Transform-Load (ETL) pipeline for health data extraction from HL7 CDA documents in Estonia for research purposes.
Methods: We developed a repeatable ETL pipeline to facilitate the extraction, cleaning, and restructuring of health data from CDA documents to OMOP CDM, ensuring a high-quality and structured data format.
Semin Nucl Med
December 2024
Mid-America Heart Institute and the Saint-Lukes Health System, University of Missouri - Kansas City, Kansas, MO. Electronic address:
Stress radionuclide myocardial perfusion imaging (MPI) has been well-established as a useful modality for assessing the status of the coronary circulation in post-coronary artery bypass graft (CABG) patients. CABG by itself escalates progression of atherosclerosis or thrombosis in bypassed native coronary arteries. In most cases MPI will be employed in post-CABG patients who are experiencing symptoms.
View Article and Find Full Text PDFHuan Jing Ke Xue
January 2025
College of Environment and Ecology, Chongqing University, Chongqing 400045, China.
Data is the core foundation of intelligent operation and maintenance, but currently, there is generally insufficient data for wastewater treatment plants, and the status of wastewater treatment systems dynamically evolves with the changes in the internal and external environment. The intelligent operation and maintenance of wastewater plants face difficulties in modeling and model drift caused by system evolution. In response to this issue, the summer and winter seasons with significant differences in wastewater temperature, wastewater quality, and microbial status were selected as typical comparison scenarios.
View Article and Find Full Text PDFInt J Clin Health Psychol
December 2024
Medical Psychological Center, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Background: Previous research has found that compulsions in obsessive-compulsive disorder (OCD) are associated with an imbalance between goal-directed and habitual responses. However, the cognitive mechanisms underlying how goal-directed and habitual behaviors are learned, and how these learning deficits affect the response process, remain unclear. The present study aimed to investigate these cognitive mechanisms and examine how they were involved in the mechanism of compulsions.
View Article and Find Full Text PDFPharmacogenomics is central to precision medicine, informing medication safety and efficacy. Pharmacogenomic diplotyping of complex genes requires full-length DNA sequences and detection of structural rearrangements. We introduce StarPhase, a tool that leverages PacBio HiFi sequence data to diplotype 21 CPIC Level A pharmacogenes and provides detailed haplotypes and supporting visualizations for HLA-A, HLA-B, and CYP2D6.
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