Several Gold's reagents were synthesized from cyanuric chloride and ,-dialkylformamides. These synthetic equivalents of ,-dimethylformamide dimethyl acetal were used in an optimized and scalable procedure for the regioselective synthesis of a variety of enaminones from ketone starting materials, whose utility was demonstrated by the stereoselective synthesis of Rawal-type dienes.
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| http://dx.doi.org/10.1016/j.tet.2017.03.092 | DOI Listing |
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