A fluorogenic probe for tracking GSH flux in developing neurons.

Chem Commun (Camb)

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.

Published: January 2020

Understanding GSH flux in developing neurons is prerequisite to reveal its role in neuronal development but necessiates an ultrasensitive assay. By systematically exploring key structural factors determing probe sensitivity in live cells, we developed a fluorogenic probe capable of imaging subtle GSH fluctuations in developing neurons.

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Source
http://dx.doi.org/10.1039/c9cc07753gDOI Listing

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