Social behaviours emerge from the exchange of information among individuals-constrained by and reciprocally influencing the structure of information flows. The Internet radically transformed communication by democratizing broadcast capabilities and enabling easy and borderless formation of new acquaintances. However, actual information flows are heterogeneous and confined to self-organized echo-chambers. Of central importance to the future of society is understanding how existing physical segregation affects online social fragmentation. Here, we show that the virtual space is a reflection of the geographical space where physical interactions and proximity-based social learning are the main transmitters of ideas. We show that online interactions are segregated by income just as physical interactions are, and that physical separation reflects polarized behaviours beyond culture or politics. Our analysis is consistent with theoretical concepts suggesting polarization is associated with social exposure that reinforces within-group homogenization and between-group differentiation, and they together promote social fragmentation in mirrored physical and virtual spaces.
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http://dx.doi.org/10.1098/rsos.190573 | DOI Listing |
J Med Internet Res
January 2025
Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, United States.
Background: Twitter (subsequently rebranded as X) is acknowledged by US health agencies, including the US Centers for Disease Control and Prevention (CDC), as an important public health communication tool. However, there is a lack of data describing its use by state health agencies over time. This knowledge is important amid a changing social media landscape in the wake of the COVID-19 pandemic.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Background: Calcineurin, a protein involved in functions such as synaptic plasticity and neuronal survival, plays an important role in the pathophysiology of Alzheimer's disease. This study, randomized, investigated the effects of FK506 (FK), a calcineurin inhibitor, on the behavioral, histological, and biochemical alterations observed in models of neurotoxicity induced by NMDA or Aβ and in a transgenic model for AD, in addition to the organotypic culture model stimulated with NMDA.
Methods: This study involved models for AD to experiment injecting NMDA or Aβ1-42 into the hippocampus of male C57Bl/6 mice aged 8-12 weeks to induce a neurotoxicity model, treating double-transgenic APP/PS1 mice, expressing both mouse/human APP and mutant human PS1, with chronic FK506 for AD, in which, to enable NMDA or Aβ1-42 microinjections, another experiment including a stereotaxic surgery was performed on the C57Bl/6 mice.
BMC Health Serv Res
January 2025
Faculty of Health Sciences, Department of Rehabilitation Science and Health Technology, OsloMet - Oslo Metropolitan University, Oslo, Norway.
Background: As the population ages, more people live longer with multimorbidity. Older people with multimorbidity face diverse needs and medical conditions, increasing the risk of adverse health outcomes, and often experience fragmented healthcare. Research has called for better ways to reach, understand and care for this group to enhance care continuity.
View Article and Find Full Text PDFHealth Expect
February 2025
Osteopathy Sciences Research Unit (URSO), Université Libre de Bruxelles (ULB), Brussels, Belgium.
Objective: Chronic musculoskeletal pain (CMSP) is frequent in chronic diseases, decreasing the quality of life of these patients. In a survey conducted in Belgium in 2019, chronic pain was named by patients as the main factor of complexity in their lives. The objective of our research was to provide elements to understand why and how CMSP contributes to the complexity of these people's lives.
View Article and Find Full Text PDFJ Pregnancy
December 2024
Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
Preinduction cervical ripening in previous caesarean pregnancy is limited to intracervical Foley catheter. This study is aimed at finding the vaginal birth rates, improvement of Bishop score, and safety of osmotic dilator (Dilapan-S) among women with previous caesarean pregnancy. We conducted this single-group clinical study after the approval of the institute ethics committee, clinical trial registration, and obtaining informed consent.
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