BURKITT LYMPHOMA IN GASTROINTESTINAL TRACT: A REPORT OF TWO CASES.

Acta Clin Croat

1Department of Gastroenterology, Rijeka University Hospital Centre, Rijeka, Croatia; 2Department of Radiotherapy and Oncology, Rijeka University Hospital Centre, Rijeka, Croatia; 3Department of Pathology, Rijeka University Hospital Centre, Rijeka, Croatia; 4Department of Neurosurgery, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 5University of Applied Health Sciences, Zagreb, Croatia.

Published: June 2019

Burkitt lymphoma, a type of non-Hodgkin B-cell lymphoma, is the fastest growing human cancer, presenting pathologically with a 'starry sky' pattern. It is most often found in the abdomen and the jaw, however, localization in the abdomen other than the ileocecal area is very rare and described only in a handful of cases. Standard treatment consists of initial tumor cytoreduction followed by intense chemotherapy. Most of the relapses occur within one year of the diagnosis, while the 5-year survival is around 80%. We present two cases which are specific for unusual location of Burkitt lymphoma in the colon and stomach, in immunocompetent patients with negative Epstein-Barr virus tests. Also, one of the patients presented is one of the oldest ever reported with abdominal Burkitt lymphoma, while the other patient is an example of diagnostic difficulties in distinguishing Burkitt lymphoma from similar lymphomas. Due to the rapidly growing tumors and urgent need for cytoreductive surgery, it is crucial to consider the diagnosis of Burkitt lymphoma even in atypical localizations or absence of the common risk factors associated with Burkitt lymphoma.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884372PMC
http://dx.doi.org/10.20471/acc.2019.58.02.25DOI Listing

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