Phages based electrochemical sensors have received much attention due to their high specificity, sensitivity and simplicity. Phages or bacteriophages provide natural affinity to their host bacteria cells and can serve as the recognition element for electrochemical sensors. It can also act as a tool for bacteria infection and lysis followed by detection of the released cell contents, such as enzymes and ions. In addition, possible detection of the other desired targets, such as antibodies have been demonstrated with phage display techniques. In this paper, the recent development of phage-based electrochemical sensors has been reviewed in terms of the different immobilization protocols and electrochemical detection techniques.
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http://dx.doi.org/10.3390/mi10120855 | DOI Listing |
Talanta
December 2024
School of Chemistry, Dalian University of Technology, Dalian, 116024, PR China. Electronic address:
The study of cell mechanics was significant for understanding cellular physiological functions, the mechanisms of disease occurrence, and the development of novel therapeutic approaches. However, research on the mechanism of mechanical strain action at the single-cell level was relatively lacking. Herein, we developed a serpentine stretchable sensor array capable of exerting precise mechanical strain on cells and monitoring extracellular pH (pHe) changes at single cell level.
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December 2024
Department of Chemistry, University of Texas at San Antonio, TX, 78249, USA. Electronic address:
Aminated carbon nanotubes, CNT, were covalently modified with glutardialdehyde (GDI) and the redox dye Azure to form a new electrode material CNT-GDI-Azure (CGA). The nanocomposite of CGA and polysaccharide chitosan was used for the anodic determination of NADH. Compared to conventional carbon and metal electrodes, the CGA electrode drastically lowered the overpotential for NADH oxidation (by > 0.
View Article and Find Full Text PDFMikrochim Acta
December 2024
Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan, 411105, People's Republic of China.
GO/Co-MOF/PPy-350 (GPC-350) was synthesized by in situ growth of ultrafine Co-MOF on graphene oxide (GO), followed by encapsulation with polypyrrole (PPy) and calcination at 350.0℃. Meanwhile, MoS-MWCNTs (MoS-CNTs) were produced via the in situ synthesis of MoS within multi-walled carbon nanotubes (MWCNTs).
View Article and Find Full Text PDFLangmuir
December 2024
Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources and International Innovation Center for Forest Chemicals and Materials, Nanjing Forestry University, Nanjing 210037, China.
This study reports the development of an innovative electrochemical sensor based on organometallic framework nanostructures for detecting valganciclovir (VLCV). VLCV is employed in the treatment of cytomegalovirus retinitis in AIDS patients. Rational design of nanoarchitectures for electroactive materials is a crucial approach for boosting their electrocatalytic performance.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Civil, Environmental and Mechanical Engineering, University of Trento, Via Mesiano, 77, 38123, Trento, Italy.
In this study, DL-phenylalanine modified with a multiwall carbon nanotube paste electrode is used as advanced electrochemical sensor for analysing of 0.1 mM caffeic acid (CFA) with simultaneous detection of riboflavin (RFN). The developed sensors include electrochemically polymerized DL-phenylalanine (DL-PA) modified multiwall carbon nanotube paste electrode [DL-PAMMCNTPE] and bare multiwall carbon nanotube paste electrode [BMCNTPE].
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