Phage-based Electrochemical Sensors: A Review.

Micromachines (Basel)

Department of Mechanical and Aerospace Engineering, Hong Kong University of Science and Technology, Hong Kong, China.

Published: December 2019

Phages based electrochemical sensors have received much attention due to their high specificity, sensitivity and simplicity. Phages or bacteriophages provide natural affinity to their host bacteria cells and can serve as the recognition element for electrochemical sensors. It can also act as a tool for bacteria infection and lysis followed by detection of the released cell contents, such as enzymes and ions. In addition, possible detection of the other desired targets, such as antibodies have been demonstrated with phage display techniques. In this paper, the recent development of phage-based electrochemical sensors has been reviewed in terms of the different immobilization protocols and electrochemical detection techniques.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952932PMC
http://dx.doi.org/10.3390/mi10120855DOI Listing

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