The medial frontal cortex has been linked to voluntary action, but an explanation of why decisions to act emerge at particular points in time has been lacking. We show that, in macaques, decisions about whether and when to act are predicted by a set of features defining the animal's current and past context; for example, respectively, cues indicating the current average rate of reward and recent previous voluntary action decisions. We show that activity in two brain areas-the anterior cingulate cortex and basal forebrain-tracks these contextual factors and mediates their effects on behavior in distinct ways. We use focused transcranial ultrasound to selectively and effectively stimulate deep in the brain, even as deep as the basal forebrain, and demonstrate that alteration of activity in the two areas changes decisions about when to act.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975166 | PMC |
| http://dx.doi.org/10.1016/j.neuron.2019.10.030 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Sand and dust storms: a growing global health threat calls for international health studies to support policy action.
Lancet Planet Health
January 2025
Chinese Center for Disease Control and Prevention, Beijing, China; Department of Epidemiology, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing, China.
Sand and dust storms increasingly threaten global environmental and public health. To date, 150 countries are directly affected, with more than 100 classified as non-dust source regions. With climate change, these storms are expected to become more frequent and severe.
View Article and Find Full Text PDFEmpowerment of volunteer nursing service providers during disasters: A qualitative study.
BMC Emerg Med
January 2025
Department of Health in Disasters and Emergencies, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran.
Background: Volunteers providing nursing services are among the first individuals to arrive at the scene after an incident; therefore, they must use their skills and capabilities to provide necessary care for the injured to prevent problems from worsening and complications from arising. Consequently, having structured empowerment courses for volunteers before disasters seems essential. This research aimed to determine the dimensions and components of empowering volunteer nursing service providers in disasters.
View Article and Find Full Text PDFThe effect of reward and voluntary choice on the motor learning of serial reaction time task.
Front Psychol
January 2025
School of Psychology, Beijing Sport University, Beijing, China.
Objective: Reward and voluntary choice facilitate motor skill learning through motivation. However, it remains unclear how their combination influences motor skill learning. The purpose of the present study is to investigate the effects of reward and voluntary choice on motor skill learning in a serial reaction time task (SRTT).
View Article and Find Full Text PDFExamining the integration of refugees into the national health system in Uganda: an analysis using the policy triangle framework.
Confl Health
January 2025
Department of Community Health and Behavioural Science, School of Public Health, College of Health Sciences, Makerere University, Mulago Hill Road, P.O. Box 7072, Kampala, Uganda.
Background: Uganda has been confronted with a sustained influx of refugees for decades. This prompted the government to explore opportunities to integrate refugees into local service structures including its national health system. This paper chronicles the history of policies and strategies that have influenced the integration of refugees into the national health system in Uganda and investigates factors that impacted policy evolution and progression.
View Article and Find Full Text PDFAreas for action to promote positive forms of masculinities in preventing violence against women: a concept mapping study in Spain.
Int J Equity Health
January 2025
Department of Community Nursing, Preventive Medicine and Public Health and History of Science, University of Alicante, Alicante, Spain.
Background: Violence against women (VAW) perpetrated by men is a public health problem of significant magnitude that negatively affects the whole society. Unequal gender relations produce differentiated positions in the social structure; gender roles that position men and women differently are defined and which are at the root of VAW. Framed within the European PositivMasc project, the aim of this study was to identify the areas for action to promote positive masculinities in preventing VAW in Spain, based on community stakeholders' perceptions on their importance and applicability.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!