Sensing the Environment: Extracellular Lactate Levels Control Adult Neurogenesis.

Cell Stem Cell

Department of Physiology, University of Lausanne, 1005 Lausanne, Switzerland. Electronic address:

Published: December 2019

Metabolism has emerged as a key player for stem cell behavior; however, the role of metabolism in the microenvironment remains poorly understood. In this issue of Cell Stem Cell, Wang et al. (2019) show that brain endothelial cells directly affect adult neural stem cells and maintain a healthy metabolic environment by regulating lactate levels.

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http://dx.doi.org/10.1016/j.stem.2019.11.008DOI Listing

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