AI Article Synopsis
- The study presents draft genome sequences for 15 isolates from the Beijing-B0/W-148 sublineage of bacteria.
- These isolates have a specific 7-base pair insertion in a gene that produces a fusion protein called Pks15/1.
- Pks15/1 plays a role in synthesizing phenolglycolipids and forming biofilms, which may increase the virulence and drug resistance of this bacterial lineage.
Article Abstract
Here, we report the draft genome sequences of 15 isolates of the Beijing-B0/W-148 sublineage that carry a 7-bp insertion within the gene, which leads to the synthesis of Pks15/1 fusion protein. Pks15/1 is involved in phenolglycolipid synthesis and biofilm formation, thus potentially contributing to the B0/W-148 lineage's enhanced virulence and drug resistance.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895303 | PMC |
| http://dx.doi.org/10.1128/MRA.01126-19 | DOI Listing |
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