, , herpes simplex virus (HSV) and human papillomavirus (HPV) cause sexually transmitted infections. In addition, human herpesvirus 6 (HHV-6) may be a genital co-pathogen. The prevalence rates of HSV, HHV-6, HPV, , and the genotypes were investigated by PCR in urogenital samples of the nucleic acid amplification test positive (n = 157) and age-, community- and time-matched negative (n = 157) women. The prevalence of HPV DNA was significantly higher among the positives than the negatives (66% vs. 25%, < 0.001). The prevalence of HSV (1.9% vs. 0%), HHV-6 (11% vs. 14%), and DNA (4.5% vs. 1.9%) was not significantly different between the -positive and -negative women. Thirteen per cent of test-of-cure specimens tested positive for . The prevalence of HSV, HHV-6, HPV, , and the genotypes did not significantly differ between those who cleared the infection (n = 105) and those who did not (n = 16). The higher prevalence of HPV DNA among the positives suggests greater sexual activity and increased risk for sexually transmitted pathogens.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963806PMC
http://dx.doi.org/10.3390/pathogens8040276DOI Listing

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