AI Article Synopsis
- Species delimitation (SD) is growing in systematics research, but different methods often lead to conflicting results when analyzing the same species.
- The authors introduce LIMES, a tool that automatically compares species classifications from various SD methods without needing a reference tree, featuring four established comparison indexes.
- LIMES is available for free download at www.limes.cnrs.fr, with additional data accessible online through Bioinformatics.
Article Abstract
Motivation: Species delimitation (SD) is on the verge of becoming a fully fledged research field in systematics, but the variety of available approaches tends to result in significant-sometimes striking-incongruences, when tested comparatively with a given taxonomic sampling.
Results: We present LIMES, an automatic calculation tool which qualitatively compares species partitions obtained by distinct SD approaches, regardless of their respective theoretical backgrounds, and even in absence of reference topology. The program implements four different previously published indexes, and allows their automated calculation.
Availability And Implementation: LIMES is freely downloadable at www.limes.cnrs.fr.
Supplementary Information: Supplementary data are available at Bioinformatics online.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/bioinformatics/btz911 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
HSPG-binding peptide Pep19-2.5 is a potent inhibitor of HPV16 infection.
Antimicrob Agents Chemother
January 2025
Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Peptide-based therapeutics are gaining attention for their potential to target various viral and host cell factors. One notable example is Pep19-2.5 (Aspidasept), a synthetic anti-lipopolysaccharide peptide that binds to heparan sulfate proteoglycans (HSPGs) and has demonstrated inhibitory effects against certain bacteria and enveloped viruses.
View Article and Find Full Text PDFAn immunocompetent human kidney on-a-chip model to study renal inflammation and immune-mediated injury.
Biofabrication
December 2024
Model Development, MIMETAS BV, De Limes 7, Oegstgeest, 2342DH, NETHERLANDS.
Kidney damage and dysfunction is an emerging health issue worldwide resulting in high morbidity and mortality rates. Numerous renal diseases are recognized to be driven by the immune system. Despite this recognition, the development of targeted therapies has been challenging as knowledge of the underlying mechanism and complex interactions remains insufficient.
View Article and Find Full Text PDFFederated difference-in-differences with multiple time periods in DataSHIELD.
iScience
November 2024
Institute for Computational Biology, Helmholtz Munich - German Research Center for Environmental Health, Munich, Germany.
Difference-in-differences (DID) is a key tool for causal impact evaluation but faces challenges when applied to sensitive data restricted by privacy regulations. Obtaining consent can shrink sample sizes and reduce statistical power, limiting the analysis's effectiveness. Federated learning addresses these issues by sharing aggregated statistics rather than individual data, though advanced federated DID software is limited.
View Article and Find Full Text PDFConcrete Crack Detection and Segregation: A Feature Fusion, Crack Isolation, and Explainable AI-Based Approach.
J Imaging
August 2024
Department of Electrical Engineering and Computer Science, Florida Atlantic University, Boca Raton, FL 33431, USA.
Scientific knowledge of image-based crack detection methods is limited in understanding their performance across diverse crack sizes, types, and environmental conditions. Builders and engineers often face difficulties with image resolution, detecting fine cracks, and differentiating between structural and non-structural issues. Enhanced algorithms and analysis techniques are needed for more accurate assessments.
View Article and Find Full Text PDFComparative analysis of adhesion virulence protein FadA from gut-associated bacteria of colorectal cancer patients () and healthy individuals ().
J Cancer
August 2024
Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Colorectal cancer (CRC) is a gastrointestinal disease linked with GIT microbial dysbiosis. The present study has targeted the comparative analysis of virulent factor FadA from gut-associated bacteria of CRC patients () and healthy individuals (). For this purpose, FadA protein sequences of fifteen strains of and four strains of , were retrieved from the UniProt database.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!