FACTORS INFLUENCING RECOVERY AFTER PANCREATODUODENECTOMY: UNICENTER EXPERIENCE.

Our purpose was to determine the incidence of pancreatic fistula (POPF) and delayed gastric emptying (DGE), assess impact of these and other potential factors of influence on overall survival. We analyzed 97 patients who underwent pancreaticoduodenectomy between 2012 and 2018 years. POPF grade B was present in 7 (7,1%) and grade C in 8 (8,2%). DGE grade B was present in 15 (15,3%) and grade C in 7 (7,1%). Patients with POPF grade C had lower OS, compared to others (p=0,0005). DGE had a significant association with POPF (χ²=9,5; p=0,003). Furthermore, we didn't prove impact of DGE grade, grade of tumor differentiation, T and N status, histological subtype (adenocarcinomas vs. other types) on OS (р=0,63, p=0,1054, p=0,7, p=0,74 and p=0,193 respectively). Therefore, POPF, especially grade C, is accompanied by a decrease in OS of patientsafter PD and is associated with DGE. DGE, tumor differentiation, T and N indices, and histological type of the tumor have no influence on OS.