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http://dx.doi.org/10.1183/13993003.02009-2019DOI Listing

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Article Synopsis
  • Tobacco flavors in various products often contain preservatives like benzoic acid and sorbic acid to prevent fungal growth, but excessive consumption of these can be harmful to health.
  • Accurate measurement of these preservatives is vital for safety, as they can lead to adverse reactions in sensitive individuals and some, like parabens, disrupt endocrine functions.
  • A new method using three phase-hollow fiber-liquid phase microextraction combined with high performance liquid chromatography has been developed to effectively analyze nine key preservatives in tobacco flavors, addressing challenges in sensitivity and operational costs of previous methods.
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