Purpose: The aim of our study using an intraoperative optical coherence tomography (iOCT) device was to assess the rate of neurosensory elevation with resulting subfoveal and extrafoveal hyporeflective zones during membrane peeling and to evaluate a possible influence on postoperative outcomes.
Procedures: This study included patients scheduled for pars plana vitrectomy with membrane peeling due to idiopathic epiretinal membrane. All patients underwent 23-G pars plana vitrectomy with iOCT-guided membrane peeling and were scheduled for follow-up examinations at 1 day, 5 days, and 3 months after surgery.
Results: Among the 171 patients included, subfoveal and extrafoveal hyporeflective zones could be detected in 12 patients (7%). Follow-up at 3 months after surgery was available for 149 patients with a median improvement in best corrected visual acuity of +2 lines (IQR: +1 to +4 lines). There were no significant differences in outcomes between patients with and those without subfoveal/extrafoveal hyporeflective zones concerning visual acuity, macular thickness, occurrence of intraretinal cystoid changes, and postoperative hyporeflective zones.
Conclusions: No significant differences in postoperative outcomes were observed between patients with and those without subfoveal/extrafoveal hyporeflective zones.
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